GLAUBRIM 2 мг/мл Глазные капли, раствор
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Инструкция по применению LAUBRIM
Содержание инструкции
Glaubrim 2 mg/ml eye drops, solution
Brimonidine tartrate
Generic medicine
Read this leaflet carefully before you start using this medicine as it contains
important information for you.
- Keep this leaflet. You may need to read it again.
- If you have any questions, ask your doctor or pharmacist.
- This medicine has been prescribed for you only. Do not pass it on to others even if they have the same symptoms as you because it may be harmful.
- If you get any side effects, even those not listed in this leaflet, tell your doctor or pharmacist. See section 4.
Contents of this leaflet:
- 1. What Glaubrim is and what it is used for
- 2. What you need to know before you use Glaubrim
- 3. How to use Glaubrim
- 4. Possible side effects
- 5. How to store Glaubrim
- 6. Contents of the pack and other information
1. What is Glaubrim and what is it used for
Glaubrim is an eye drop and each bottle contains 5 ml of the medicine.
The active ingredient of Glaubrim is Brimonidine tartrate.
Glaubrim is used to reduce the pressure inside the eye in patients with glaucoma or
ocular hypertension (high pressure in the eye).
2. What you need to know before you use Glaubrim
Do not use Glaubrim:
- If you are allergic to brimonidine tartrate or any of the other ingredients of this medicine listed in section 6;
- If you are taking monoamine oxidase inhibitors (MAO) e.g. phenelzine or isocarboxazide which are often used to treat depression;
- If you are taking tricyclic antidepressants (e.g. amitriptyline, imipramine) or mianserine which are often used to treat depression.
- If you are breastfeeding or intend to do so.
- In newborns or infants (from birth to 2 years).
Warnings and precautions
Talk to your doctor or pharmacist before using Glaubrim if:
- you suffer from or have suffered from depression, reduced blood flow to the brain, heart problems, blood pressure disorders or poor blood supply to the limbs;
- you have or have had kidney or liver problems in the past;
- you use soft (hydrophilic) contact lenses.
Children and adolescents under 17 years of age
Glaubrim should not be used in children under 2 years of age.
Glaubrim is not recommended in children (from 2 to 12 years).
Clinical studies have not been conducted with Glaubrim in adolescents (12-17 years).
Other medicines and Glaubrim
Before using Glaubrim tell your doctor or pharmacist if you have any other eye conditions and
also if you are taking, have recently taken or might take any other medicine in
particular:
- painkillers (e.g. co-codamol), sedatives (anti-stress or sleeping drugs e.g. diazepam or alprazolam), opioids (e.g. morphine), barbiturates (e.g. phenobarbital) or if you are a regular alcohol consumer;
- medicines to treat depression (e.g. fluoxetine, paroxetine or venlafaxine), treat heart conditions (e.g. digoxin) or to lower blood pressure (e.g. bendroflumethiazide, atenolol, lisinopril or reserpine);
- prazosin, a medicine often used to treat enlarged prostate;
- chlorpromazine and methylphenidate, often used to treat certain nervous disorders.
Tell your doctor or pharmacist if you are taking or have recently taken any medicine
including medicines obtained without a prescription or if the dosage of any of
the medicines you are taking regularly has changed.
Pregnancy, breastfeeding and fertility
Ask your doctor or pharmacist for advice before taking any medicine. If you are pregnant, suspect or are planning a pregnancy or if you are breastfeeding with breast milk,
ask your doctor or pharmacist for advice before taking this medicine. Glaubrim should
be used in pregnancy only if specifically recommended by your doctor. Do not use Glaubrim if
you are breastfeeding or intend to do so.
Driving and operating machinery
In some patients Glaubrim may cause drowsiness or fatigue. It can also cause blurred/altered vision; these effects may seem worse at night or in poor lighting conditions. Wait until these effects have disappeared before driving vehicles or
operating machinery.
Glaubrim containsthe preservative benzalkonium chloride which can cause eye irritation and is
known to cloud soft contact lenses.
3. HOW TO USE GLAUBRIM
Use this medicine following exactly the instructions of your doctor. If you have any doubts, ask your
doctor or pharmacist.
Avoid contact with soft contact lenses. If you wear soft contact lenses, remove the lenses
before using Glaubrim and then wait at least 15 minutes before applying them again.
The recommended dose is one drop twice a day in the affected eye(s), approximately
12 hours apart (for example once in the morning and once in the evening).
If you use Glaubrim with another eye drop, wait 5 to 15 minutes before applying the second
eye drop.
Use in children and adolescents under 17 years
Glaubrim should not be used in children under 2 years of age.
Glaubrim is not recommended in children (from 2 to 12 years).
Clinical studies with Glaubrim in adolescents (12-17 years) have not been conducted.
Instructions for use:
Glaubrim is for external use as an eye drop only, do not ingest.
Always wash your hands before applying eye drops. Apply one drop of Glaubrim to each
affected eye as follows:
- 1. Tilt your head back and look up.
- 2. Gently lower the lower eyelid to form a small pocket.
- 3. Turn the bottle upside down and press it lightly to release one drop of eye drop into each eye to be treated.
- 4. Keep the treated eye closed, pressing your finger against the inner corner for about 1 minute.
- 5. Screw the cap back on immediately after use.
Avoid touching the tip of the bottle to the eye or anything else.
If you use more Glaubrim than you should
If you have instilled too many drops of Glaubrim into your eye(s), it is unlikely that this
will cause any harm. Apply the next dose at the usual time. In case of ingestion
contact your doctor immediately as it may cause low blood pressure, high blood pressure, reduced cognitive ability, low heart rate, decreased muscle tone, respiratory blockage and decreased body temperature, symptoms that may
require hospitalisation.
If you forget to use Glaubrim
If you forget to take a dose, take it as soon as you remember. However, if it is already time to
apply the next dose, skip the missed dose and apply the next dose following the
normal administration times. The dose should not exceed one drop twice a day
in the affected eye(s).
If you stop taking Glaubrim
Do not stop treatment with this medicine without first informing your doctor.
4. POSSIBLE SIDE EFFECTS
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Stop using Glaubrim and contact your doctor immediatelyif you notice any of these symptoms (general allergic reactions):
- Swelling of the face, tongue or throat
- Difficulty swallowing
- Skin rashes or difficulty breathing
Very common: may affect more than 1 in 10 people
- Allergic reaction in the eye, follicles or white spots on the eyes, blurred vision, red eye, burning, stinging, foreign body sensation or itching
- Headache, dry mouth and fatigue/drowsiness
Common: may affect up to 1 in 10 people
- Changes in the surface of the eye, redness, swelling, pain and sensitivity of the eye or eyelids, altered vision, sticky eyes, sensitivity to light, irritation, dryness, tearing or whitening of the eye.
- Dizziness, flu-like symptoms, gastrointestinal symptoms, altered taste or general weakness
Uncommon: may affect up to 1 in 100 people
- Depression, palpitations (feeling of heartbeat), change in heartbeat, dry nose and general allergic reactions
Rare: may affect up to 1 in 1,000 people
- Shortness of breath
Very rare: may affect up to 1 in 10,000 people
- Inflammation in the eye or reduction in pupil size
- Insomnia, fainting and high or low blood pressure
Some of these effects may be due to allergic reactions to one of the ingredients of Glaubrim.
If any of these side effects gets serious, or if you notice any side effect not listed in this leaflet, tell your doctor or pharmacist.
Reporting of side effects
If you get any side effects, even those not listed in this leaflet, tell your doctor or pharmacist. You can also report side effects directly through the national reporting system at
http://www.agenziafarmaco.gov.it/it/responsabili .
By reporting side effects you can help provide more information on the safety of this medicine.
5. How to store Glaubrim
Keep out of sight and reach of children.
Do not use the bottle if the safety seal of the bottle is broken before first use.
Do not use Glaubrim after the expiry date which is stated on the bottle label and on the packaging
after Exp. The expiry date refers to the last day of that month.
Do not use the same bottle 28 days after first opening, even if it is not yet empty.
Do not store the bottle at a temperature above 25 ˚ C.
Keep the bottle in the outer packaging to protect it from light.
Do not dispose of any medicine in the drain or household waste. Ask your pharmacist how
to dispose of medicines you no longer use. This will help protect the environment.
6. Contents of the pack and other information
What Glaubrim contains
- The active substance of Glaubrim is brimonidine tartrate 2 mg/ml equivalent to brimonidine 1.3 mg/ml.
- The other ingredients are: benzalkonium chloride (preservative), polyvinyl alcohol, sodium chloride, sodium citrate, citric acid monohydrate, water for injections, sodium hydroxide or hydrochloric acid (for pH adjustment).
Description of the appearance of Glaubrim and contents of the pack
Glaubrim is a clear solution with a colour ranging from yellowish-green to slightly yellowish-green
in a plastic bottle containing 5 ml of solution.
Glaubrim is available in packs of 1, 2 or 3 bottles.
Not all pack sizes may be marketed in all countries.
Marketing Authorisation Holder and Manufacturer
Marketing Authorisation Holder:
Farmigea SpA Via G.B. Oliva, 8 – 56121 Pisa, Italy
Manufacturer:
Farmigea SpA Via G.B. Oliva, 8 – 56121 Pisa, Italy
This medicinal product is authorised in the Member States of the European Economic Area with the
following denominations:
This leaflet was last revised in MM/YYYY
| United Kingdom | Brymont 0.2% (2mg/ml) Eye drops, solution |
| Sweden | Brymont 0.2% (2mg/ml) Eye drops, solution |
| Norway | Brymont 0.2% (2mg/ml) Eye drops, solution |
| Poland | Brymont 0.2% (2mg/ml) Eye drops, solution |
| Italy | Glaubrim 0.2% (2mg/ml) eye drops, solution |
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- Страна регистрации
- Форма выпускаEye drops, solution, 2MG/ML
- Код АТХS01EA05
- Действующее вещество
- Отпускается по рецептуДа
- Производитель
- Информация на этой странице носит справочный характер и не является медицинской консультацией. Перед началом приема лекарства обязательно проконсультируйтесь с врачом.
- Аналоги LAUBRIMФорма выпуска: Eye drops, solution, 2,5 MLДействующее вещество: БримонидинПроизводитель: ABBVIE S.R.L.Отпускается по рецептуФорма выпуска: Eye drops, solution in single-dose container, 2 MG/MLДействующее вещество: БримонидинПроизводитель: OMNIVISION ITALIA SRLОтпускается по рецептуФорма выпуска: Eye drops, solution, 2 MG/MLДействующее вещество: БримонидинПроизводитель: BRUSCHETTINI S.R.L.Отпускается по рецепту
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Часто задаваемые вопросы
LAUBRIM требует рецепта в Италия. Вы можете уточнить у врача онлайн, подходит ли это лекарство для вашей ситуации.
Действующее вещество LAUBRIM — Бримонидин. Эта информация помогает определить лекарства с тем же составом под другими торговыми названиями.
LAUBRIM производится компанией FARMIGEA S.P.A.. Упаковка и торговое название могут отличаться в зависимости от дистрибьютора.
Врачи, включая Семейные врачи, Психиатры, Дерматологи, Кардиологи, Эндокринологи, Гастроэнтерологи, Пульмонологи, Нефрологи, Ревматологи, Гематологи, Инфекционисты, Аллергологи, Гериатры, Педиатры, Онкологи, могут оценить целесообразность применения LAUBRIM с учетом вашей ситуации и местных правил. Вы можете записаться на онлайн-консультацию, чтобы обсудить возможные варианты.
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Другие лекарства с тем же действующим веществом (Бримонидин) включают ALPAGAN, BRIMOFREE, BRIMOFTAL. Они могут отличаться торговым названием или формой выпуска, но содержат одинаковый терапевтический компонент. Перед изменением лечения рекомендуется проконсультироваться с врачом.
