ENALAPRIL 20 mg /12.5 Mg Коированная Таблетка

Содержание инструкции

1. ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH 20 mg/12.5 mg tablets
   1. WHAT IS ENALAPRIL HYDROCHLOROTHIAZIDE SANDOZ GMBH AND WHAT IS IT USED FOR
   2. BEFORE TAKING ENALAPRIL HYDROCHLOROTHIAZIDE SANDOZ GMBH
   3. HOW TO TAKE ENALAPRIL HYDROCHLOROTHIAZIDE SANDOZ GMBH
   4. POSSIBLE SIDE EFFECTS
   5. HOW TO STORE ENALAPRIL HYDROCHLOROTHIAZIDE SANDOZ GMBH
   6. OTHER INFORMATION
2. ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH 20mg/12,5 mg is presented in the form of tablets
3. ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH 20mg/12,5 mg is available in packs of 10, 14,

ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH 20 mg/12.5 mg tablets

Generic medicine
Read this leaflet carefully before using this medicine

• Keep this leaflet. You may need to read it again.
• If you have any questions, ask your doctor or pharmacist.
• This medicine has been prescribed for you personally. Never give it to others. Indeed, this medicine may be dangerous for other individuals, even if their symptoms are the same as yours.
• If any of the side effects worsen, or if you notice any side effect not listed in this leaflet, tell your doctor or pharmacist.

Contents of this leaflet:

• 1. What ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH is and what it is used for
• 2. Before you take ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH
• 3. How to take ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH
• 4. Possible side effects
• 5. How to store ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH
• 6. Further information

1. WHAT IS ENALAPRIL HYDROCHLOROTHIAZIDE SANDOZ GMBH AND WHAT IS IT USED FOR

Enalapril, which belongs to a group of medicines called angiotensin converting enzyme inhibitors (ACE inhibitors), lowers blood pressure by widening blood vessels.

Hydrochlorothiazide, which belongs to a group of medicines called diuretics, lowers blood pressure by increasing diuresis (elimination of urine).
ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH tablets contain a combination of enalapril and hydrochlorothiazide and are used to treat high blood pressure (hypertension) when treatment with enalapril alone as a single agent has proven insufficient.
Your doctor may also prescribe ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH tablets instead of separate tablets at the same doses of enalapril and hydrochlorothiazide.
This fixed-dose combination is not suitable for starting therapy.

2. BEFORE TAKING ENALAPRIL HYDROCHLOROTHIAZIDE SANDOZ GMBH

DO NOT take ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH

• if you are allergic (hypersensitive) to enalapril maleate, hydrochlorothiazide or any of the other ingredients of this medicine;
• if you are allergic (hypersensitive) to sulfonamide derivatives (mainly antibiotics, such as sulfamethoxazole);
• if you have previously experienced swelling of the extremities, face, lips, throat, mouth or tongue (angioedema) while being treated with other medicines belonging to a class of drugs called ACE inhibitors (angiotensin converting enzyme inhibitors);
• if you have previously experienced, in any other circumstance, swelling of the extremities, face, lips, throat, mouth or tongue (angioedema)
• if a relative of yours has previously experienced swelling of the extremities, face, lips, throat, mouth or tongue (angioedema);
• if you suffer from severe kidney disorders;
• if you are unable to urinate
• if you suffer from severe liver disorders or a neurological disorder due to severe liver problems (hepatic encephalopathy);
• if you are pregnant for more than three months (it is best to avoid Enalapril Hydrochlorothiazide Sandoz GmbH even in the early stages of pregnancy - see section Pregnancy);

Take particular care with ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH
Before starting treatment with this medicine, inform your doctor in the following cases:

• if you suffer from a narrowing of the arteries (atherosclerosis), cerebrovascular disorders, such as a stroke or transient ischemic attack (TIA, a “mini-stroke”);
• if you suffer from a disease characterized by reduced blood supply to the heart muscle, usually due to coronary artery disease (ischemic heart disease)
• if you suffer from heart failure;
• if you have low blood pressure, are following a low-salt diet or are taking diuretics;
• if you have abnormal levels of water and mineral salts in the body (hydro/electrolyte imbalance) characterized especially by nausea, abdominal cramps and/or vomiting, headache, edema (swelling), muscle weakness and/or tremor;
• if you suffer from a heart muscle disease (hypertrophic cardiomyopathy), a narrowing of the aorta, the main artery that carries blood from the heart (aortic stenosis), or suppression of the artery of the only functioning kidney, have undergone a kidney transplant or other forms of a heart condition called outflow obstruction;
• if you are going to undergo LDL-apheresis (removal of cholesterol from the blood using a special device);
• if you are going to undergo desensitization therapy for the venom of some insects, such as bee and wasp stings;
• if you suffer from diabetes;
• if you suffer from gout, have high levels of uric acid in the blood or are undergoing treatment with allopurinol;
• if you are about to receive anesthesia;
• if you have recently suffered from prolonged and severe vomiting and/or severe diarrhea;
• if you are about to undergo tests of parathyroid function;
• if you suffer from or have suffered from liver or kidney disorders or a narrowing of the renal arteries (renal artery stenosis), or if you have only one functioning kidney, or if you are undergoing hemodialysis;
• if you suffer from collagen vascular diseases, such as systemic lupus erythematosus (SLE) or scleroderma, which may be associated with skin rashes, joint pain and fever;
• if you are taking, among others, a medicine capable of suppressing the immune response (immunosuppressant) or procainamide, which is used to treat heart rhythm disorders
• if you have had skin cancer in the past or if you are developing an unexpected skin lesion during treatment. Treatment with hydrochlorothiazide, especially long-term use with high doses, may increase the risk of some types of skin cancer and lips (non-melanoma skin cancer). Protect your skin from exposure to the sun and UV rays while taking ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH
• if you have allergy or asthma problems.
• if you are taking lithium, used for the treatment of some psychiatric illnesses

If you believe you are (or may become) pregnant, inform your doctor. ENALAPRIL
HYDROCHLOROTHIAZIDE Sandoz GmbH is not recommended in the early stages of pregnancy and should not
be used after the first trimester, as it could seriously harm the baby (see
section “Pregnancy and breastfeeding”). Breastfeeding is not recommended during the intake of
ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH.
Generally ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH is not recommended in the cases described below, therefore consult your doctor before taking this medicine:

• if you have recently undergone a kidney transplant;
• if you have too much potassium in your blood, potassium levels must be checked during treatment. Risk factors for higher potassium levels include impaired kidney function, age (>70 years), dehydration, acute heart failure, metabolic acidosis, diabetes mellitus, concomitant use of diuretics, potassium supplements or salt substitutes containing potassium, or taking medicines that increase potassium concentration in the blood. A decrease in potassium levels in the blood is also possible, characterized by high blood pressure, heart rhythm disturbances, etc. (for example caused by drug interactions, excessive urine loss, etc.). Also refer to the section “Taking ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH with other medicines” below.

If you are an athlete and have to undergo a doping test, consult your doctor, as ENALAPRIL
HYDROCHLOROTHIAZIDE Sandoz GmbH contains an active ingredient that may determine positive results.
Elderly patients (>70 years) or malnourished patients should be particularly careful when using
ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH.
ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH may be less effective in black patients.
The use of this medicine is not recommended in children.
If you develop any of the following symptoms during treatment with ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH, inform your doctor immediately:

• experience dizziness after taking the first dose. Some people react to taking the first dose or to an increase in the dosage with symptoms such as dizziness, weakness, fainting and nausea;
• develop a sudden swelling of the lips, face and neck, which may also affect hands and feet, or shortness of breath or hoarseness: these are the symptoms of a condition called angioedema, which may occur at any time during treatment. ACE inhibitors cause a higher incidence of angioedema in black patients compared to non-black patients;
• develop a high temperature, sore throat or ulcers in the mouth (these may be symptoms of an infection caused by a decrease in the number of white blood cells);
• experience yellowing of the skin and whites of the eyes (jaundice), which may be a sign of a liver disorder;
• develop a dry cough that lasts a long time. Cough has been reported following the use of ACE inhibitors, but it may also be a symptom of another disease of the upper respiratory tract.
• Sudden myopia
• If you have decreased vision or eye pain. These may be symptoms of fluid accumulation in the vascular layer of the eye (choroidal effusion) or increased pressure in the eye and can occur within hours to weeks of taking Enalapril Hydrochlorothiazide Sandoz. This can lead to permanent vision loss if left untreated. If you have previously had an allergy to penicillin or sulfonamides, you may be at greater risk of developing this.

Taking ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH with other medicines
You must not take ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH at the same time as the following
medicines:

• potassium supplements or salt substitutes containing potassium
• diuretics, used to treat high blood pressure, including potassium-sparing diuretics such as spironolactone, triamterene or amiloride
• other medicines used to treat high blood pressure
• anesthetics and medicines used for mental disorders or depression, medicines used to treat psychosis, tricyclic antidepressants or sedatives
• lithium (a medicine for the treatment of psychiatric disorders)
• pain relievers and anti-inflammatory drugs, such as acetylsalicylic acid or indomethacin
• gold salts (sodium aurothiomalate), an injectable medicine used for rheumatoid arthritis
• medicines such as ephedrine, used in some cough and cold remedies, or norepinephrine and epinephrine, used to treat low blood pressure, shock, heart failure, asthma or allergies
• medicines that lower blood sugar levels, for example insulin or oral antidiabetics
• cholestyramine and colestipol resins, active ingredients used to lower blood fat levels
• corticosteroids, hormone-like anti-inflammatory substances
• Corticotropin (ACTH), used to check the correct functioning of the adrenal glands
• muscle relaxants (for example, tubocurarine chloride, medicines used to relax muscles during surgical operations)
• allopurinol, probenecid, sulfinpyrazone, medicines used to treat gout
• medicines such as atropine or biperidene, which are used to treat a variety of disorders, such as gastrointestinal cramps, bladder spasms, asthma, motion sickness and muscle spasms, and as adjuvants during anesthesia
• cancer medicines, such as cyclophosphamide or methotrexate
• medicines that inhibit the immune system, medicines used to prevent rejection reactions after an organ or bone marrow transplant
• cyclosporine, a medicine used to prevent rejection reactions after an organ or bone marrow transplant
• cardiac glycosides (for example, digoxin), medicines used to strengthen the heart
• medicines that, as a side effect, can cause abnormalities in the conduction of the cardiac stimulus, such as medicines used for heart rhythm disorders, some medicines used for psychosis and other medicines used to treat bacterial infections
• calcium salts and vitamin D, high levels of calcium in the blood (can lead to gastrointestinal disorders, excessive thirst, excessive urination, fatigue, weakness and weight loss).
• carbamazepine, a medicine mainly used for the treatment of epilepsy and bipolar disorder
• amphotericin B, a medicine used for the treatment of fungal infections
• laxatives, medicines used to facilitate bowel movements
• iodinated contrast agents, which increase the visibility of vascular structures and organs during radiographic procedures.
• barbiturates, which act as central nervous system depressant medicines, causing sedation
• opioid analgesics, potent pain relievers without anti-inflammatory effect
• carbenoxolone, a medicine for treating inflammation of the gastrointestinal tract
• salicylates, medicines for the treatment of pain and/or inflammatory diseases

If you are taking or have recently taken other medicines, including over-the-counter medicines and
herbal or natural products, tell your doctor or pharmacist.

Taking ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH with food and drink
ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH can be taken with or without
meals. Drinking alcohol in conjunction with this medicine may increase the blood pressure lowering effect (and may therefore cause, among other effects, dizziness when getting up).

Pregnancy and breastfeeding
Ask your doctor or pharmacist for advice before taking any medicine.

Pregnancy
If you believe you are (or may become) pregnant, inform your doctor, who will generally advise you to stop treatment with ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH before
becoming pregnant or as soon as pregnancy has been diagnosed and to take another medicine
instead of ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH. ENALAPRIL HYDROCHLOROTHIAZIDE
Sandoz GmbH is not recommended in the early stages of pregnancy and should not be used after the first
trimester, as it may seriously harm the baby.

Breastfeeding
Tell your doctor if you are breastfeeding or considering starting breastfeeding. ENALAPRIL
HYDROCHLOROTHIAZIDE Sandoz GmbH is not recommended for mothers who are breastfeeding.

Driving and operating machinery
Patients treated with ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH have reported dizziness and
fatigue: if you experience any of these symptoms, refrain from driving vehicles and operating
machinery (see also section 4, “Possible side effects”).

Important information about some excipients of ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH
Patients intolerant to lactose should be informed that the tablets of ENALAPRIL
HYDROCHLOROTHIAZIDE Sandoz GmbH contain a small amount of lactose. If your doctor has
diagnosed you with an intolerance to some sugars, consult him before taking this medicine.

3. HOW TO TAKE ENALAPRIL HYDROCHLOROTHIAZIDE SANDOZ GMBH

Always take ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH exactly as your doctor has prescribed.
If you have any doubts, ask your doctor or pharmacist.

Adults
The normal dose is one tablet once a day.

Elderly
Your doctor may decide to carefully adjust the dose of enalapril and hydrochlorothiazide.

Kidney problems
Your doctor will carefully adjust the dose of enalapril and hydrochlorothiazide.

Method of administration
The tablets should be swallowed with a sip of water.
ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH can be taken with or without food.
The score line is only to facilitate breaking the tablet to aid swallowing and not to
divide it into two equal halves.

If you take more ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH than you should
If you (or someone else) have taken many tablets of ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH
all at once or if you think a child has swallowed one or more tablets, seek immediate
medical assistance. An overdose is likely to cause low blood pressure,
excessive increase or decrease in heart rate, palpitations (the feeling that the
heartbeat is excessively fast or irregular), shock, rapid breathing, cough, nausea and vomiting,
cramps, dizziness, drowsiness and confusion or anxiety, excessive urination (passing of urine) or inability to
remaining tablets and the packaging of the medicine, so that they can know which and how many
tablets have been taken.

If you forget to take ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH
Do not take a double dose of ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH to make up for
forgetting a tablet; simply take the next dose as usual.
If you have any further questions about using this medicine, ask your doctor or pharmacist.

If you stop taking ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH
Treatment for hypertension is long-term and stopping it should be discussed with your doctor.
Stopping or interrupting treatment may cause an increase in blood pressure.
If you have any further questions about using this medicine, ask your doctor or pharmacist.

4. POSSIBLE SIDE EFFECTS

Like all medicines, ENALAPRIL IDROCLOROTIAZIDE Sandoz GmbH can cause side
effects, although not everybody gets them.

If you experience any of the following side effects, stop taking ENALAPRIL
IDROCLOROTIAZIDE Sandoz GmbH and immediately inform your doctor or go to the nearest
hospital emergency room:

• a severe allergic reaction called angioedema (skin rash, itching, swelling of the extremities, face, lips, mouth or throat, which can cause difficulty swallowing or breathing). This is a serious and common side effect (affecting more than 1 in 100 patients and less than 1 in 10). You may need urgent medical attention or hospitalisation;
• jaundice (yellowing of the skin and the whites of the eyes). This is a potentially serious but rare side effect (affecting more than 1 in 10,000 patients and less than 1 in 1000), indicative of liver inflammation. You may need urgent medical attention or hospitalisation.
• Sudden myopia. The frequency of this side effect is not known (cannot be defined based on available data)
• Decreased vision or eye pain due to high pressure (possible signs of fluid accumulation in the vascular layer of the eye (choroidal effusion) or acute angle-closure glaucoma). The frequency of this side effect is not known (cannot be defined based on available data)

ENALAPRIL IDROCLOROTIAZIDE Sandoz GmbH commonly causes low blood pressure, which can be
associated with a feeling of lightheadedness and weakness. In some patients, this symptom may occur
with the first dose or when the dose is increased. If you experience these symptoms, contact your
doctor immediately.
ENALAPRIL IDROCLOROTIAZIDE Sandoz GmbH rarely causes a decrease in the number of
white blood cells in the blood, which may reduce your resistance to infections. If
you develop an infection with symptoms such as fever and a general worsening of your condition, or fever
with symptoms of local infection, such as sore throat/pharynx/mouth, or urinary disorders, contact
your doctor immediately. You will be given a blood test to check for a possible
decrease in white blood cells (agranulocytosis). It is important that you inform your doctor that you are taking
this medicine.
Very commonly (in more than 1 in 10 patients) dry cough has been reported following the use of ENALAPRIL IDROCLOROTIAZIDE Sandoz GmbH and other ACE inhibitors, which may persist for a long time and
which may also be a symptom of another upper respiratory tract disorder. If you develop
this symptom, you should contact your doctor.
The following side effects have also been reported:

Very common(more than 1 in 10)

• blurred vision
• dizziness
• nausea
• weakness

Common (more than 1 in 100 but less than 1 in 10)

• low level of potassium in the blood, which can cause muscle weakness, spasms or abnormal heart rhythm
• high level of fat or uric acid in the blood
• headache, depression
• fainting, low blood pressure associated with changes in posture (for example a feeling of lightheadedness or weakness when getting up from lying down), chest pain, changes in heart rate, excessively fast heartbeat (tachycardia)
• shortness of breath
• diarrhoea, abdominal pain
• changes in the sense of taste
• skin rash
• fatigue
• elevated levels of potassium in the blood, which can cause heart rhythm abnormalities; increased amount of creatinine in the blood.
• muscle cramps

Uncommon (more than 1 in 1000 but less than 1 in 100)

• reduction in the number of red blood cells in the blood, which can make the skin pale and cause weakness or difficulty breathing (anaemia)
• hypoglycaemia (low blood sugar levels - see “Pay special attention to ENALAPRIL IDROCLOROTIAZIDE Sandoz GmbH especially in the following cases”, paragraph 2)
• low levels of magnesium in the blood
• uric acid crystals in the joints (gout)
• confusion, drowsiness, insomnia, nervousness, tingling or numbness, vertigo, decreased sexual desire
• palpitations (the sensation that the heartbeat is fast or particularly strong or irregular)
• heart attack or stroke (“mini stroke”) (mainly in patients who suffer from low blood pressure)
• runny nose, sore throat, hoarseness, difficulty breathing, dyspnoea
• intestinal obstruction, inflammation of the pancreas, which causes severe pain in the abdomen and back (pancreatitis), vomiting, indigestion, constipation, loss of appetite, gastric irritation, dry mouth, peptic ulcer, flatulence
• sweating, itching, urticaria, hair loss
• joint pain
• kidney disorders, presence of protein in the urine
• impotence
• hot flushes, ringing in the ears
• malaise, fever
• low levels of sodium in the blood, which can cause fatigue and confusion, muscle spasms, convulsions or coma, and also dehydration and low blood pressure, which in turn can cause dizziness when getting up; increased amount of urea in the blood.

Rare (more than 1 in 10,000 but less than 1 in 1000)

• reduction in the number of white blood cells, which facilitates the onset of infections, reduction in the number of other blood cells, changes in blood composition, poor bone marrow production, lymph node disease, autoimmune disease, due to which the body attacks itself
• strange dreams, sleep disorders
• paresis
• Raynaud's syndrome, a disorder of the blood vessels that can cause tingling of the fingers of the hands and feet, which become pale, then bluish, then reddish
• lung disorders, including pneumonia, inflammation of the lining of the nose, which begins to run (rhinitis)
• mouth ulcers, inflammation of the tongue
• liver disorders, inflammation of the gallbladder
• skin rash, appearance of severe blisters, redness of the skin, Stevens-Johnson syndrome (blisters on the skin, in the mouth, in the eyes and on the genitals), skin that looks burned and peels off, sensitivity of the skin to light, skin conditions with scaly red spots on the nose and cheeks (lupus erythematosus), pemphigus (a disorder that causes blisters and lesions that usually begin in the mouth, urticaria, hair loss and itching). Sometimes, skin problems may be accompanied by fever, severe inflammation, inflammation of the blood vessels, muscle and/or joint pain, changes in blood composition and increased erythrocyte sedimentation rate (a blood test used to identify inflammation)
• decreased urine production
• kidney inflammation (interstitial nephritis)
• breast enlargement in men
• increased levels of enzymes and waste substances produced by the liver
• increased blood sugar levels

Very rare (less than 1 in 10,000)

• intestinal swelling
• elevated levels of calcium in the blood (see “Pay particular attention to Enalapril Hydrochlorothiazide Sandoz GmbH in paragraph 2)

Not known (cannot be estimated on the basis of available data)

• inappropriate secretion of the antidiuretic hormone (known as SIADH) which causes, among others, general symptoms such as confusion, nausea, mood changes, convulsions and loss of consciousness
• skin and lip cancer (non-melanoma skin cancer)

Further side effects:

• inflammation of a salivary gland
• excretion of glucose in the urine (glycosuria)
• decreased appetite, feeling of lightheadedness
• predominance of a yellow vision due to the yellowing of the eye (xanthopsia)

If any of these side effects gets worse, or if you notice any side effect

5. HOW TO STORE ENALAPRIL HYDROCHLOROTHIAZIDE SANDOZ GMBH

Keep ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH out of the reach and sight of children.
Do not store at a temperature above 30°C. Store in the original package.
Do not use ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH after the expiry date, which is reported
on the outer packaging.
Do not use ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH after the expiry date (EXP), which is
indicated on the label. The expiry date refers to the last day of the month.
Medicines should not be disposed of via drains or household waste. Ask your pharmacist how to
dispose of medicines you no longer use. This will help protect the environment.

6. OTHER INFORMATION

What ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH contains

• The active ingredients are enalapril maleate and hydrochlorothiazide.
• Each tablet contains 20 mg of enalapril maleate and 12.5 mg of hydrochlorothiazide.
• The excipients are: sodium hydrogen carbonate, corn starch, lactose monohydrate, calcium hydrogen phosphate dihydrate, talc and magnesium stearate.

Description of the appearance of ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH and contents of the
pack

ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH 20mg/12,5 mg is presented in the form of tablets

white, oval and biconvex, with a fracture line on one side and the inscription “E H” on the other.

ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH 20mg/12,5 mg is available in packs of 10, 14,

20, 28, 30, 49, 50, 50x1, 60, 98, 100 and 120 tablets.
It is possible that not all packs are marketed

Marketing Authorisation Holder and Manufacturer
Marketing Authorisation Holder
Sandoz GmbH – Biochemiestrasse, 10 – 6250 Kundl (Austria)
Representative for Italy: Sandoz Spa – Largo U. Boccioni, 1 – 21040 Origgio (VA)

Manufacturer responsible for batch release
SALUTAS Pharma GmbH - Otto-von-Guericke-Allee, 1 - 39179 Barleben (Germany)

This medicinal product has been authorised in the EEA member states with the following denominations:
Netherlands: Enalaprilmaleaat/ Hydrochloorthiazide Sandoz 20/12.5 mg, tablets
Belgium: Co- Enalapril Sandoz 20/ 12,5 mg tablets
Denmark: Corodil comp
Finland: LINATIL-HEXAL COMP 20 mg/12.5 mg tablets
Germany: EnaHEXAL comp 20mg/12,5mg Tablets
Italy: ENALAPRIL HYDROCHLOROTHIAZIDE Sandoz GmbH 20 mg/12.5 mg tablets
Norway: Enalapril/hydrochlorthiazid HEXAL
Portugal: Enalapril + Hidroclorotiazida Sandoz 20 mg + 12.5 mg Comprimidos
United Kingdom: Enalapril + HCT 20mg/12.5mg Tablets
Spain: ENALAPRIL-HIDROCLOROTIAZIDA BEXAL 20/12.5 mg comprimidos EFG
Sweden: Linatil comp