NOXAFIL 40 mg /Ml Zawiesina Doustna
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Jak stosować NOXAFIL
Treść ulotki
the user
should ask the doctor, pharmacist or nurse.
what is Noxafil and
what is
“antifungals”. It is used to prevent and treat many different types of infections
- “ ” “ ”
- infections of the mouth or throat (known as “thrush”) caused by fungi called
high risk of contracting a fungal infection, such as:
- patients who have a weakened immune system due to chemotherapy for “acute myeloid leukemia” (AML) or “myelodysplastic syndromes” (MDS)
- use a “high-dose immunosuppressive therapy” following “hematopoietic stem cell transplantation” (HSCT).
- medicine that contains “alkaloids derived from ergot” such as ergotamine or dihydroergotamine or a “statin” such as simvastatin, atorvastatin or lovastatin.
See below “Other medicines and Noxafil” for more information including information on the
- develops severe diarrhea or vomiting, as these conditions can limit the effectiveness of this
- is taking vincristine, vinblastine or other “vinca alkaloids” (medicines used for
- ’
’
’
- contains “alkaloids derived from ergot” such as ergotamine or for the treatment of migraine
- a “statin”
- ’
The following medicines may decrease the effectiveness of Noxafil by decreasing
- and fosamprenavir used for the treatment of HIV infection.
- vincristine, vinblastine and other “vinca alkaloids” (used for the treat
- medicines used for the treatment of HIV called protease inhibitors (including lopinavir and
- midazolam, triazolam, alprazolam or other “benzodiazepines” (used as sedatives or
- diltiazem, verapamil, nifedipine, nisoldipine or other “calcium channel blockers” (used for the treatment
- digoxin (used for the treatment of heart failure)
- glipizide or other “sulfonylureas” (used for the
“ ”
- Swallow the tablet whole with water.
at the hospital
’
’
’
Tell your doctor, pharmacist or nurse if you notice any of the following side effects
- goosebumps, tingling
- of “neutrophils” -
- “white blood cells”
- “eosinophils” a type of white blood cells (eosino - an inflammation
- interruption of oxygen supply to the spleen (splenic infarction) -
- bleeding in the stomach or intestines -
- in the intestine (intestinal obstruction) the “ ” contents of the intestine to pass into the lower part of the intestine -
- “hemolytic uremic syndrome” when red blood cells
- “pancytopenia” a low level of all blood cells (red blood cells and white blood cells and
- alterations of the
- ’
’
to your doctor, pharmacist or nurse.
the national reporting system reported in the
on the label
the expiry date refers to the last day
Do not dispose of any medicine in the drain
This will help protect the environment.
Description of the appearance of Noxafil and contents of the pack
Marketing Authorization Holder
of the marketing authorization:
България
Merck Sharp & Dohme Bulgaria EOOD
Tel.: +359 2 819 3737
Česká republika
Ελλάδα
Α.Φ.Ε.Ε.
Τηλ
á
Κύπρος
Τηλ.: 800 00 673
’
more detailed information on this medicine is available on the Agency website and
the user
’
should ask the doctor, pharmacist or nurse. See section 4.
what is Noxafil and what it is used for
what is
called “antifungals”. It is used to prevent and treat many different types of infections
- known as “chromoblastomycosis” and “mycetoma” that have not improved during treatment with itraconazole or when you are
who are at high risk of contracting an infection
- weakened immune system due to chemotherapy for “acute myeloid leukemia” (AML) or “myelodysplastic syndromes” (MDS)
- use a “high-dose immunosuppressive therapy” following “hematopoietic stem cell transplantation” (HSCT).
- “alkaloids derived from ergot” such as dihydroergotamine or a “statin” such as simvastatin, atorvastatin or lovastatin.
See below “Other medicines and Noxafil” for information on other medicines that may
- is taking vincristine, vinblastine or other “vinca alkaloids” (medicines used for
- During treatment, avoid exposure to the sun. It is important to cover areas of the skin
pharmacist or nurse before using Noxafil.
- “alkaloids derived from ergot” such as
- a “statin” such as simvastatin, atorvastatin or lovastatin
- ’
’
- ’
- vincristine, vinblastine and other “vinca alkaloids” (used for the treatment of tumors)
- ’
- midazolam, triazolam, alprazolam or other “benzodiazepines” (used as
- diltiazem, verapamil, nifedipine, nisoldipine or other “calcium channel blockers” (used for the treatment
- ’
- glipizide or other “sulfonylureas” (used for the treatment of high levels of
’
or the nurse.
If you have any doubts about using this medicine, ask your doctor, pharmacist or
nurse.
’
Inform your doctor, pharmacist or nurse if you notice any of the following side effects:
- ’
- low levels of “neutrophils” a type of -
- low level of “leukocytes”
- high level of “eosinophils” - an inflammation
- interruption of oxygen supply to the spleen (splenic infarction) -
- ’ -
- ’ ’“ileus”. The blockage will prevent the ’ ’ -
- “hemolytic uremic syndrome” when red blood cells
- “pancytopenia” a low level
- alterations of the
- ’s intake
Inform your doctor, pharmacist or nurse if you notice
to the doctor, to the pharmacist or to the nurse
the national reporting system reported in the
on the label
’
–
–
refrigerator). This medicine is for single use only and the even
’
’
’
variations in color within this chromatic range do not affect the quality of the product.
’authorization for the placing on the
’ ’
България
Merck Sharp & Dohme Bulgaria EOOD
Tel
Česká
Ελλάδα
Α Φ Ε Ε
Τηλ
Κύπρος
Tel.: 800 00 673 (+357 22866700)
’
’
within approximately 90
the infusion must be administered within approximately 30
’
variations in color within this chromatic range do not alter the quality of the p
’
- ’
- ’
’
What is Noxafil and what is it used for
called “antifungals”. It is used to prevent and treat many different varieties of infect
- me “chromoblastomycosis” and “mycetoma” that have not improved during treatment with itraconazole or when you are
who are at high risk of contracting a fungal infection, such as:
- due to chemotherapy for “acute myeloid leukemia” (AML) or “myelodysplastic syndromes” (MDS
- who are using a “high-dose immunosuppressive therapy” following “hematopoietic transplantation” (HSCT).
- quinidine, any medicine containing “ergot alkaloids” such as ergotamine or a “statin” such as simvastatin, atorvastatin or lovastatin.
See below “Other medicines and oxafil” for more information including information on the
or to the nurse before taking Noxafil
- develops severe diarrhea or vomiting, as these conditions can limit the effectiveness of this
- is taking vincristine, vinblastine or other “vinca alkaloids” (medicines used for the
- eve avoid exposure to the sun. It is important to cover the areas of skin
to the
’nurse,
Alcohol can affect the absorption of this medicine.
- containing “ergot alkaloids” such as ergotamine or migraine. Noxafil can increase the amount of
- a “statin” such as simvastatin, atorvastat
- ’
The following medicines can decrease the effectiveness of Noxafil by decreasing the
- and fosamprenavir used for the treatment of HIV infection.
- tri “vinca alkaloids” (used for the
- ll’HIV called protease inhibitors (including lopinavi
- midazolam, triazolam, alprazolam or other “benzodiazepines”
- diltiazem, verapamil, nifedipine, nisoldipine or other “calcium antagonists” (used for the treatment
- digoxin (used for the treatment of heart failure)
- glipizide or other “sulfonylureas” (used for the treatment of high blood sugar levels)
and, that is essentially “without
sodium”.
Do not pass from taking Noxafil
ll’taking Noxafil
- ’ the booklet the booklet
- rima of use
- guarantee the delivery of the dose co
| Weight (kg) | Dose (volume) |
| 10-< 12 kg | 90 mg (3 mL) |
| 12-< 17 kg | 120 mg (4 mL) |
| 17-< 21 kg | 150 mg (5 mL) |
| 21-< 26 kg | 180 mg (6 mL) |
| 26-< 36 kg | 210 mg (7 mL) |
| 36-40 kg | 240 mg (8 mL) |
seek immediate medical attention
’use of this medicine, contact your doctor, pharmacist or
’nurse.
or the nurse if you notice any
mi the doctor, the pharmacist or the nurse if you notice any of the following side effects:
- goosebumps, tingling
- of “neutrophils” a type of -
- “leukocytes”
- high level of “eosinophils” a type of white blood cells (eosinophilia) - an inflammation
- interruption of oxygen supply to the spleen (splenic infarction) -
- bleeding in the stomach or intestine -
- blockage in the intestine (intestinal obstruction) especially in the “ileus”. The blockage will prevent the contents of the intestine from passing into the lower part of the intestine -
- “hemolytic uremic syndrome” when red
- “pancytopenia” a low level of all blood cells (red blood cells and white blood cells and platelets)
- alterations of hearing
- rsi confused after taking Noxafil
Inform your doctor, pharmacist or the
to the pharmacist or to the nurse.
reporting system reported in the
expiry date refers to the last day of that month.
in the drain and household waste. Ask your pharmacist
how to dispose of medicines you no longer use. This will help protect the environment
the booklet instructions for use on how to dispose of in a
The other component is
Description of the appearance of Noxafil and contents of the pack
Holder of the marketing authorization and p
ell’marketing authorization:
България
Merck Sharp & Dohme Bulgaria EOOD
Tel.: +359 2 819 3737
Česká republika
Ελλάδα
Α.Φ.Ε.Ε.
Τηλ
á
Κύπρος
Tel.: 800 00 673 (+357 22866700)
’i
More detailed information on this medicine is available on the website of the Agency and
Instructions for Use
Instructions for Use
- that you have read and understood these instructions for use
- o o o o
at the beginning
- •
- Instructions for use •
- •
- • for use with Noxafil
- remove any air bubbles from the syringe. Air bubbles can affect the
- Position the bottle adapter over the bottle with the small hole facing up.
- the bottle adapter all the way down.
- Once positioned, the bottle adapter remains in the bottle.
what you need
inside a
tt it and start over
- in the bottle adapter
- the bottle and the syringe. With the other hand,
Check for air bubbles
- serrated facing up.
move any air bubbles
- to expel the air.
- Use the amount of dose in ‘mL’ prescribed by the doctor.
content inside
12. Check for air bubbles
- serrated edge facing upwards.
expel any air bubbles
- to release the air.
- inside the child's mouth
touches the inside of the cheek
- If the child vomits or spits up the entire dose within 15 minutes of taking Noxafil, a
- to the air.
- After you have used the last sachet of Noxafil in this box, you will have a resid
AND MARKETING AUTHORISATIONS
In light of the available data in the literature on interaction with flucloxacillin and considering a
plausible mechanism of action, the PRAC believes that a decrease in plasma concentrations
of posaconazole is due to an interaction
and marketing authorisations
’
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- Kraj rejestracji
- Postać farmaceutycznaOral suspension, 40 MG/ML
- Kod ATCJ02AC04
- Substancja czynna
- Wymaga receptyNie
- Producent
- Te treści mają charakter wyłącznie informacyjny i nie zastępują konsultacji lekarskiej.
- Zamienniki NOXAFILPostać farmaceutyczna: Enteric-coated tablet, 100 MGSubstancja czynna: posaconazoleProducent: ACCORD HEALTHCARE, S.L.U.Wymaga receptyPostać farmaceutyczna: Oral suspension, 40 MG/MLSubstancja czynna: posaconazoleProducent: ACCORD HEALTHCARE, S.L.U.Bez receptyPostać farmaceutyczna: Enteric-coated tablet, 100 MGSubstancja czynna: posaconazoleProducent: biocon pharma malta i limitedWymaga recepty
Odpowiedniki NOXAFIL w innych krajach
Leki z tą samą substancją czynną dostępne w innych krajach.
Odpowiednik NOXAFIL w Hiszpania
Odpowiednik NOXAFIL w Polska
Odpowiednik NOXAFIL w Ukraina
Lekarze online w sprawie NOXAFIL
Omów stosowanie NOXAFIL, bezpieczeństwo i ocenę zasadności recepty zgodnie z obowiązującymi przepisami.
Uzyskaj receptę na NOXAFIL online
Wypełnij 2-minutowy formularz
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Lekarz analizuje Twój przypadek
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Odbierz w dowolnej aptece
Recepta elektroniczna wysłana na Twój e-mail — ważna w całej Polsce.
Często zadawane pytania
NOXAFIL nie wymaga recepty w Włochy. Możesz skonsultować się z lekarzem online, aby sprawdzić, czy ten lek może być odpowiedni w Twojej sytuacji.
Substancją czynną w NOXAFIL jest posaconazole. Informacja ta pomaga rozpoznać leki o tym samym składzie, ale pod różnymi nazwami handlowymi.
NOXAFIL jest produkowany przez MERCK SHARP & DOHME B.V.. Nazwy handlowe i opakowania mogą się różnić w zależności od dystrybutora.
Lekarze, tacy jak Lekarze rodzinni, Psychiatrzy, Dermatolodzy, Kardiolodzy, Endokrynolodzy, Gastroenterolodzy, Pulmonolodzy, Nefrolodzy, Reumatolodzy, Hematolodzy, Zakaźnicy, Alergolodzy, Geriatrzy, Pediatrzy, Onkolodzy, mogą ocenić, czy stosowanie NOXAFIL jest odpowiednie w Twoim przypadku, w zależności od sytuacji klinicznej i lokalnych przepisów. Możesz umówić konsultację online, aby omówić objawy i możliwe dalsze kroki.
Polska posiada dobrze rozwiniętą infrastrukturę ochrony zdrowia w dużych miastach, takich jak Warszawa, Kraków, Wrocław i Gdańsk. Apteki są łatwo dostępne i działają zgodnie z obowiązującymi przepisami, zapewniając dostęp do leków na receptę.
Możesz kupić NOXAFIL w Warszawie, Krakowie, Wrocławiu lub Gdańsku w każdej aptece, posiadając ważną receptę.
Aby uzyskać receptę, możesz skorzystać z Oladoctor:
Inne leki zawierające tę samą substancję czynną (posaconazole) to m.in. POSAKONATSOLO AKKORD, POSAKONATSOLO AKL, POSAKONATSOLO BIOKON. Mogą one różnić się nazwą handlową lub postacią, ale zawierają ten sam składnik terapeutyczny. Przed zmianą lub rozpoczęciem nowego leku skonsultuj się z lekarzem.
