Інструкція із застосування DEFERIPRONE LIPOMED
Зміст інструкції
Deferiprone Lipomed 500 mg film-coated tablets
deferiprone
Read this leaflet carefully before taking this medicine as it contains important information for you.
- Keep this leaflet. You may need to read it again.
- If you have any questions, ask your doctor or pharmacist.
- This medicine has been prescribed for you only. Do not pass it on to others, even if they have the same symptoms as you, as it may be harmful.
- If you get any side effects, even those not listed in this leaflet, tell your doctor or pharmacist. See section 4.
- You will find a patient card in the folding box. Fill in the card, read it carefully and carry it with you. If you experience symptoms of infection, such as fever, sore throat and flu-like symptoms, give this card to your doctor.
Contents of this leaflet:
- 1. What Deferiprone Lipomed is and what it is used for
- 2. What you need to know before you take Deferiprone Lipomed
- 3. How to take Deferiprone Lipomed
- 4. Possible side effects
- 5. How to store Deferiprone Lipomed
- 6. Contents of the pack and other information
1. What is Deferiprone Lipomed and what it is used for
Deferiprone Lipomed contains the active ingredient deferiprone. Deferiprone Lipomed is an iron chelator, a type of medicine that removes excess iron from the body.
Deferiprone Lipomed is used in the treatment of iron overload caused by
frequent blood transfusions in patients with major thalassemia, when current chelating therapy is contraindicated or inadequate.
2. What you need to know before you take Deferiprone Lipomed
Do not take Deferiprone Lipomed
- if you are allergic (hypersensitive) to deferiprone or to any of the other ingredients of this medicine (listed in section 6);
- if you have had repeated episodes of neutropenia (low number of a type of white blood cells (neutrophils)) in the past;
- if you have suffered from agranulocytosis (very low number of a type of white blood cells (neutrophils)) in the past;
- if you are currently taking medicines that cause neutropenia or agranulocytosis (see section “Other medicines and Deferiprone Lipomed”);
- if you are pregnant or breastfeeding.
Warnings and precautions
The most serious possible side effect during the intake of Deferiprone Lipomed is a very low number of a type of white blood cells (neutrophils). This condition, called severe neutropenia or
agranulocytosis, occurred in 1 – 2 people out of 100 among those who took deferiprone in
clinical studies. Because white blood cells help fight infections, a low number of
neutrophils can put you at risk of developing serious and potentially life-threatening infections (life-threatening). To monitor neutropenia during the treatment period with Deferiprone
Lipomed, the doctor will ask you to undergo a blood test (to check the
count of your white blood cells) regularly, with weekly frequency. It is very important that you attend all
these appointments. Consult the patient leaflet contained in the foldable box. Contact your
doctor immediately if you experience symptoms of infection, such as fever, sore throat and flu-like symptoms. Your white blood cell count must be checked within 24 hours to detect a
possible agranulocytosis.
If you are HIV positive, or if liver or kidney function is severely impaired, the doctor
may recommend additional checks.
The doctor will also ask you to undergo tests to monitor the amount of iron.
In addition, they may also ask you to undergo biopsies (taking small samples) of the liver.
Consult your doctor or pharmacist before taking Deferiprone Lipomed.
Other medicines and Deferiprone Lipomed
Do not take medicines that cause neutropenia or agranulocytosis (see section “Do not take
Deferiprone Lipomed”). Tell your doctor or pharmacist if you are taking, have recently taken or
may take any other medicines, including those without a prescription.
Do not take aluminum-based antacids at the same time as taking Deferiprone Lipomed.
Consult your doctor or pharmacist before taking vitamin C together with Deferiprone Lipomed.
Pregnancy and breastfeeding
Deferiprone Lipomed can harm the fetus if taken during pregnancy. Deferiprone Lipomed should not
be taken during pregnancy unless strictly necessary. If you are pregnant or become pregnant
during treatment with Deferiprone Lipomed, consult your doctor immediately.
Patients of both sexes are advised to take due precautions in sexual activity
where there is a possibility of pregnancy. Women of childbearing potential are recommended to
use an effective method of contraception during treatment with Deferiprone Lipomed and for 6 months
after the last dose. Men are recommended to use an effective method of contraception during
treatment and for 3 months after the last dose. Consult your doctor about this.
You should not use Deferiprone Lipomed if you are breastfeeding. Consult the patient leaflet
contained in the foldable box.
Driving and using machines
This medicine does not impair or negligibly impairs the ability to drive vehicles and operate
machinery.
Deferiprone Lipomed contains sodium
This medicine contains less than 1 mmol (23 mg) of sodium per tablet and is
therefore essentially sodium-free.
3. How to take Deferiprone Lipomed
Take this medicine following the instructions of your doctor exactly. If you have any doubts, ask your
doctor or pharmacist. The amount of Deferiprone Lipomed you take will depend on your weight. The
usual dose is 25 mg/kg, 3 times a day, for a total daily dose of 75 mg/kg. This latter should not exceed
100 mg/kg. Take the first dose in the morning. Take the second dose at
noon. Take the third dose in the evening. Deferiprone Lipomed can be taken with or without
food; however, you may find it easier to remember to take Deferiprone Lipomed if you take it
with meals.
If you take more Deferiprone Lipomed than you should
No cases of acute deferiprone overdose have been reported. Contact your doctor if you accidentally take a
dose higher than the one prescribed.
If you forget to take Deferiprone Lipomed
Deferiprone Lipomed will be most effective if you take all the prescribed doses. If you miss a
single dose, take it as soon as you remember and then take the next dose regularly. If you miss more than
one dose, do not take a double dose to make up for the forgotten dose; continue with the normal
schedule for taking the medicine. Do not change the daily dose of the medicine without first
talking to your doctor.
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
The most serious side effect of Deferiprone Lipomed is a very marked reduction in the number of
a type of white blood cells (neutrophils). This condition, called severe neutropenia or agranulocytosis, has
occurred in 1 - 2 people out of 100 among those who took deferiprone in clinical studies. A
reduction in the number of white blood cells may be associated with a serious and potentially fatal
infection (life-threatening). Immediately report to your doctor any symptoms of infection
such as: fever, sore throat or flu-like symptoms.
Very common side effects(may affect more than 1 in 10 people):
- abdominal pain
- nausea
- vomiting
- reddish/brown urine
If you have nausea or vomiting, taking Deferiprone Lipomed with food may help. Discoloration of
urine is a very common effect and is not harmful.
Common side effects(may affect up to 1 in 10 people):
- low number of white blood cells (agranulocytosis and neutropenia)
- headache
- diarrhoea
- increased liver enzymes
- fatigue
- increased appetite
Not known(frequency cannot be estimated from available data):
- allergic reactions including rash or tingling
Episodes of pain and swelling in the joints in varying forms from mild pain in one or more
joints to severe disability. In most cases the pain has disappeared by continuing
to take deferiprone.
Further side effects in children
In post-marketing experience with deferiprone, neurological disorders (such as tremors, walking
disorders, double vision, involuntary muscle contractions, problems with coordination of movements) have been reported in children who had been intentionally
prescribed for several years a dose equal to more than 2 times the maximum recommended dose of
100 mg/kg/day. These disorders have also been observed in children with standard doses of deferiprone.
These symptoms have disappeared after stopping deferiprone.
Reporting of side effects
If you get any side effects, talk to your doctor or pharmacist. This includes any side effects not listed in this leaflet. You can also report side effects directly through the national reporting system listed in Annex V. By reporting side effects you can help provide more information on the safety of this medicine.
5. How to store Deferiprone Lipomed
Keep this medicine out of sight and reach of children.
Do not store at a temperature above 25°C.
Do not use this medicine after the expiry date which is stated on the label and on the packaging after
Exp. The expiry date refers to the last day of that month.
Do not dispose of any medicine in wastewater or household waste. Ask your pharmacist how to
dispose of medicines you no longer use. This will help protect the environment.
6. Contents of the pack and other information
What Deferiprone Lipomed contains
The active ingredient is deferiprone. Each film-coated tablet contains 500 mg of
deferiprone.
The other ingredients are:
Tablet core: hypromellose, sodium croscarmellose (see section 2 “Deferiprone
Lipomed contains sodium”), anhydrous colloidal silicon dioxide, microcrystalline cellulose, magnesium stearate
Coating: hypromellose, macrogol 6 000, titanium dioxide
Description of the appearance of Deferiprone Lipomed and contents of the pack
Deferiprone Lipomed 500 mg tablets are white or off-white, with a shiny surface, oval
and film-coated. The tablets are marked with a central line and are
divisible into two parts. Deferiprone Lipomed is packaged in blisters of 100 film-coated
tablets each.
Marketing Authorisation Holder and Manufacturer
Lipomed GmbH
Hegenheimer Strasse 2
79576 Weil am Rhein
Germany
Telephone: +49 7621 1693 472
Fax: +49 7621 1693 474
E-mail: [email protected]
More detailed information on this medicinal product is available on the website of the European
Medicines Agency: http://www.ema.europa.eu .

- Країна реєстрації
- Лікарська формаFilm-coated tablet, 500 MG
- Код АТХV03AC02
- Діюча речовина
- Потрібен рецептТак
- Виробник
- Ця інформація надана лише для ознайомлення і не є медичною порадою. Рішення щодо лікування завжди приймає лікар.
- Альтернативи до DEFERIPRONE LIPOMEDЛікарська форма: Film-coated tablet, 500 MGДіюча речовина: ДеферипронВиробник: DOC GENERICI SRLПотрібен рецептЛікарська форма: Film-coated tablet, 500 MGДіюча речовина: ДеферипронВиробник: CHIESI FARMACEUTICI S.P.A.Рецепт не потрібенЛікарська форма: Film-coated tablet, 90 MGДіюча речовина: ДеферасироксВиробник: Abdi Farma GmbHПотрібен рецепт
Аналоги DEFERIPRONE LIPOMED в інших країнах
Препарати з тією самою діючою речовиною, доступні в інших країнах.
Аналог DEFERIPRONE LIPOMED у Іспанія
Лікарі онлайн щодо DEFERIPRONE LIPOMED
Застосування, безпека та можливість призначення рецепта — за результатами медичної оцінки.
Отримайте рецепт на DEFERIPRONE LIPOMED онлайн
Заповніть форму за 2 хвилини
Розкажіть про симптоми, історію хвороби та потрібний препарат.
Оберіть лікаря або ми призначимо
Оберіть спеціаліста або ми підберемо найближчого доступного лікаря.
Лікар розглядає ваш випадок
Зазвичай протягом 30 хвилин. Може ставити уточнювальні запитання в чаті.
Отримайте в будь-якій аптеці
Електронний рецепт надсилається на вашу пошту — дійсний по всій Польщі.
Часті запитання
DEFERIPRONE LIPOMED потребує рецепта в Італія. Ви можете обговорити з лікарем онлайн, чи підходить цей лікарський засіб для вашої ситуації.
Діюча речовина у DEFERIPRONE LIPOMED — Деферипрон. Це допомагає визначити препарати з тим самим складом, але під іншими торговими назвами.
DEFERIPRONE LIPOMED виробляється компанією LIPOMED GMBH. Назва бренду та упаковка можуть відрізнятися залежно від дистрибʼютора.
Лікарі, зокрема Сімейні лікарі, Психіатри, Дерматологи, Кардіологи, Ендокринологи, Гастроентерологи, Пульмонологи, Нефрологи, Ревматологи, Гематологи, Інфекціоністи, Алергологи, Геріатри, Педіатри, Онкологи, можуть оцінити доцільність застосування DEFERIPRONE LIPOMED з урахуванням вашого стану та місцевих правил. Ви можете записатися на онлайн-консультацію, щоб обговорити симптоми та можливі подальші кроки.
Польща має добре розвинену систему охорони здоров'я у великих містах, таких як Варшава, Краків, Вроцлав і Гданськ. Аптеки широко доступні та працюють відповідно до чинного законодавства, забезпечуючи доступ до рецептурних препаратів.
Ви можете придбати DEFERIPRONE LIPOMED у Варшаві, Кракові, Вроцлаві або Гданську в будь-якій аптеці за наявності дійсного рецепта.
Щоб отримати рецепт, ви можете скористатися Oladoctor:
Інші препарати з тією самою діючою речовиною (Деферипрон) включають DEFERIPRONE DOK, FERRIPROX, DEFERASIROX ABDI. Вони можуть відрізнятися торговою назвою або формою випуску, але містять той самий терапевтичний компонент. Перед зміною або початком прийому нового препарату варто проконсультуватися з лікарем.
















