Инструкция по применению SILIMARIN
Содержание инструкции
SILIMARIN 200 mg coated tablets
Silimarina
Read this leaflet carefully before taking this medicine because
it contains important information for you.
- Keep this leaflet. You may need to read it again.
- If you have any questions, ask your doctor or pharmacist.
- This medicine has been prescribed for you only. Do not pass it on to others, even if they have the same symptoms as you, as it may be harmful.
- If you experience any side effects, including those not listed in this leaflet, tell your doctor or pharmacist. See section 4.
Contents of this leaflet:
- 1. What SILIMARIN is and what it is used for
- 2. What you need to know before you take SILIMARIN
- 3. How to take SILIMARIN
- 4. Possible side effects
- 5. How to store SILIMARIN
- 6. Contents of the pack and other information
1. What is SILIMARIN and what is it used for
SILIMARIN contains the active ingredient silymarin, which belongs to the class of drugs
used for liver therapies.
SILIMARIN is used as supportive treatment for symptoms related to digestive disorders, feeling of fullness and indigestion, and supportive treatment for
liver function after serious conditions have been clinically ruled out.
2. What you need to know before you take SILIMARIN
Do not take SILIMARIN
- If you are allergic to silymarin or any of the other ingredients of this medicine listed in section 6.
- If allergic to plants of the Asteraceae (Composite) family
- If there is a physical obstruction in the bile ducts.
Warnings and precautions
Talk to your doctor or pharmacist before taking SILIMARIN.
If symptoms worsen during use of the medicine, consult your doctor. If jaundice or a change in the color of urine or stools occurs, you must
consult your doctor immediately.
Children and adolescents
The efficacy and safety of use in children and adolescents under 18
years of age have not been established due to a lack of adequate data.
SILIMARIN contains sodium
This medicine contains less than 1 mmol (23 mg) of sodium per tablet, i.e.
essentially “sodium-free”.
Other medicines and SILIMARIN
Tell your doctor or pharmacist if you are taking, have recently taken or
may take any other medicines, including those not prescribed by your doctor.
No interactions with other drugs have been reported, although it has been observed
that silymarin decreases the activity of cytochrome P450, of UDP-glucuronosyltransferase
(UGT) and reduces the activity of P-gp.
Pregnancy and breastfeeding
If you are pregnant, suspect you may be pregnant or are planning a pregnancy, or if you
are breastfeeding, ask your doctor or pharmacist for advice before
taking this medicine.
Do not use SILIMARIN during pregnancy and breastfeeding unless in case of
absolute necessity and after informing your doctor who will assess whether the potential benefits
outweigh the possible risks.
Driving and using machines
SILIMARIN does not alter or negligibly alters the ability to drive vehicles or
use machines.
3. How to take SILIMARIN
Take this medicine following exactly the instructions of your doctor or pharmacist.
If you have any doubts, consult your doctor or pharmacist.
The recommended dose is 200 mg twice a day after meals, for 4-6 weeks.
Always inform your doctor during treatment because the administration and dosage are purely indicative and may be increased at the doctor's discretion.
Once improvement is achieved, your doctor may reduce the dose to be taken to 200 mg per
day.
If you take more SILIMARIN than you should
In case of accidental ingestion/intake of an excessive dose of Silimarin, immediately inform your doctor or go to the nearest hospital.
If you have any doubts about the use of Silimarin, consult your doctor or pharmacist.
If you forget to take SILIMARIN
Do not take a double dose to make up for the missed tablet.
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everyone will experience them.
If you experience any of the following side effects, stop taking your
tablets and inform your doctor immediately.
Rare (may affect up to 1 in 1,000 people)
- stomach and intestinal disorders (gastrointestinal disorders);
- soft stools (laxative effect).
Very rare (may affect up to 1 in 10,000 people)
- alteration of breathing rate and rhythm (dyspnea);
- rash with blisters accompanied by redness, itching and pain (skin rash);
- allergic reactions (hypersensitivity reactions).
Frequency not known(the frequency of which cannot be defined on the basis of available
data):
- dry mouth
- nausea
- stomach discomfort
- gastric irritation
- headache
- dermatitis
- urticaria
- itching
- anaphylaxis (sudden and severe allergic reaction with difficulty breathing, swelling, dizziness, rapid heartbeat, sweating and loss of consciousness)
- asthma
Reporting of side effects
If you experience any side effects, including those not listed in this
leaflet, please inform your doctor or pharmacist. You can also report side effects
directly through the national reporting system at
https://www.aifa.gov.it/content/segnalazioni-reazioni-avverse .
By reporting side effects you can help provide more information
about the safety of this medicine.
5. How to store SILIMARIN
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the label after
“Exp.”.
The expiry date refers to the last day of that month. The expiry date
indicated refers to the product in intact packaging, correctly stored.
This medicine does not require any particular precautions for storage.
Do not dispose of any medicine in wastewater or household waste. Ask your
pharmacist how to dispose of medicines you no longer use. This will help to
protect the environment.
6. Contents of the pack and other information
What SILIMARIN contains
The active ingredient is silymarin.
One coated tablet contains:
Active ingredient:extract (as dry extract) from the fruit of milk thistle (22-27:1).
Extraction solvent: 95% (v/v) acetone. Each tablet contains 200 mg of
total flavonoids expressed as silymarin.
Excipients:corn starch, mannitol, microcrystalline cellulose, methylcellulose,
magnesium stearate.
Coating excipients:cetyl alcohol, ethylcellulose, hypromellose, polyethylene glycol
400, polysorbate 80, sodium lauryl sulfate, titanium dioxide, triacetin (glyceryl triacetate).
Description of the appearance of SILIMARIN and contents of the pack
Coated tablets.
SILIMARIN is available in packs of 30 coated tablets containing 200 mg in blisters.
Marketing Authorisation Holder and Manufacturer
ELLEVA PHARMA S.r.l., Via San Francesco n. 5/7, 80034 Marigliano (NA)
MANUFACTURER
Special Product’s Line S.p.A.
Strada Paduni, 240
03012 Anagni (FR)
Italy
LACHIFARMA SRL, LABORATORIO CHIMICO FARMACEUTICO SALENTINO
S.S. 16 Zona Industriale
73010 Zollino (LE)
Italy

- Страна регистрации
- Форма выпускаCoated tablet, <200 mg
- Код АТХA05BA03
- Действующее вещество
- Отпускается по рецептуДа
- Производитель
- Информация на этой странице носит справочный характер и не является медицинской консультацией. Перед началом приема лекарства обязательно проконсультируйтесь с врачом.
- Аналоги SILIMARINФорма выпуска: Granulate, 200 MGДействующее вещество: СилимаринПроизводитель: PHARMABER S.R.L.Отпускается по рецептуФорма выпуска: Hard capsule, 250 MGДействующее вещество: chenodeoxycholic acidПроизводитель: LEADIANT GMBHОтпускается по рецептуФорма выпуска: Hard capsule, 250 MGДействующее вещество: урсодезоксихолевая кислотаПроизводитель: ABC FARMACEUTICI S.P.A.Отпускается по рецепту
Аналоги SILIMARIN в других странах
Лекарства с тем же действующим веществом, доступные в других странах.
Аналог SILIMARIN в Польша
Аналог SILIMARIN в Украина
Аналог SILIMARIN в Испания
Врачи онлайн по SILIMARIN
Обсудите применение SILIMARIN и возможные следующие шаги — по оценке врача.
Получите рецепт на SILIMARIN онлайн
Заполните форму за 2 минуты
Расскажите о симптомах, истории болезни и нужном препарате.
Выберите врача или мы назначим
Выберите специалиста или мы подберём ближайшего доступного врача.
Врач рассматривает ваш случай
Обычно в течение 30 минут. Может задать уточняющие вопросы в чате.
Получите в любой аптеке
Электронный рецепт отправляется на вашу почту — действителен по всей Польше.
Часто задаваемые вопросы
SILIMARIN требует рецепта в Италия. Вы можете уточнить у врача онлайн, подходит ли это лекарство для вашей ситуации.
Действующее вещество SILIMARIN — Силимарин. Эта информация помогает определить лекарства с тем же составом под другими торговыми названиями.
SILIMARIN производится компанией ELLEVA PHARMA SRL. Упаковка и торговое название могут отличаться в зависимости от дистрибьютора.
Врачи, включая Семейные врачи, Психиатры, Дерматологи, Кардиологи, Эндокринологи, Гастроэнтерологи, Пульмонологи, Нефрологи, Ревматологи, Гематологи, Инфекционисты, Аллергологи, Гериатры, Педиатры, Онкологи, могут оценить целесообразность применения SILIMARIN с учетом вашей ситуации и местных правил. Вы можете записаться на онлайн-консультацию, чтобы обсудить возможные варианты.
Польша имеет хорошо развитую систему здравоохранения в крупных городах, таких как Варшава, Краков, Вроцлав и Гданьск. Аптеки широко доступны и работают в соответствии с действующим законодательством, обеспечивая доступ к рецептурным препаратам.
Вы можете купить SILIMARIN в Варшаве, Кракове, Вроцлаве или Гданьске в любой аптеке при наличии действующего рецепта.
Чтобы получить рецепт, вы можете воспользоваться Oladoctor:
Другие лекарства с тем же действующим веществом (Силимарин) включают SILMAR, AKIDO KENODESOSSIKOLIKO LEADIANT, AKIDO URSODESOSSIKOLIKO ABK. Они могут отличаться торговым названием или формой выпуска, но содержат одинаковый терапевтический компонент. Перед изменением лечения рекомендуется проконсультироваться с врачом.
















