Інструкція із застосування BIORINIL
Зміст інструкції
BIORINIL 0.05% + 0.1% nasal spray, suspension
Betamethasone + Tetrizoline hydrochloride
Read this leaflet carefully before you start using this medicine as it contains
important information for you.
- Keep this leaflet. You may need to read it again.
- If you have any questions, ask your doctor or pharmacist.
- This medicine has been prescribed for you only. Do not pass it on to others, even if their symptoms are the same as yours, as it may be harmful.
- If you get any side effects, even those not listed in this leaflet, tell your doctor or pharmacist. See section 4.
Contents of this leaflet:
- 1. What BIORINIL is and what it is used for
- 2. What you need to know before you use BIORINIL
- 3. How to use BIORINIL
- 4. Possible side effects
- 5. How to store BIORINIL
- 6. Contents of the pack and other information
1. What is BIORINIL and what is it used for
BIORINIL nasal spray, suspension is a preparation containing betamethasone, a steroid with
anti-inflammatory action and tetrizoline hydrochloride, a vasoconstrictor, which constricts small blood
vessels.
BIORINIL is indicated in adults and adolescents over the age of 12for the
treatment of acute and subacute rhinitis, sinusitis, nasopharyngitis.
See your doctor if you do not feel better or if you feel worse.
2. What you need to know before using BIORINIL
Do not use Biorinil if:
- you are allergic to the active ingredients or any of the other ingredients of this medicine (listed in section 6),
- you suffer from glaucoma,
- you suffer from enlarged prostate (prostatic hypertrophy),
- you suffer from severe heart disease,
- you suffer from high blood pressure (hypertension),
- you suffer from excessive production of thyroid hormones (hyperthyroidism),
- you suffer from severe kidney failure,
- you are taking or have taken therapy with antidepressants in the 2 weeks prior,
- you suffer from tuberculosis, fungal (mycotic) and viral infections of the mucous membranes to be treated.
- you are under the age of 12
Warnings and precautions
Consult your doctor or pharmacist before using Biorinil.
In particular, inform your doctor if:
- you suffer from cardiovascular and metabolic endocrine disorders.
- you experience blurred vision or other visual disturbances. In patients with cardiovascular diseases and especially in hypertensive patients, the use of nasal decongestants must be assessed by a doctor each time.
Possible undesirable effects of topical products
The use, especially if prolonged, of a topical product may lead to sensitization.
Possible undesirable effects of preparations containing vasoconstrictors for prolonged periods
Prolonged use of preparations containing vasoconstrictors may alter the normal function of the
nasal and paranasal sinus mucosa, also inducing drug habituation. Repeating the
applications for long periods can therefore be harmful.
Do not use for more than 4 consecutive days in any case.
Children
Do not give Biorinil to children under 12 years of age.
Other medicines and Biorinil
Tell your doctor or pharmacist if you are taking, have recently taken or might
take any other medicine.
Due to the presence of tetrizoline, the product should not be administered to patients undergoing treatment
with antidepressants (monoamine oxidase inhibitors).
Pregnancy and breastfeeding
Use BIORINIL during pregnancy only if absolutely necessary, under direct medical supervision.
Ask your doctor or pharmacist for advice before taking any medicine.
Driving and using machines
BIORINIL does not impair the ability to drive vehicles or operate machinery.
BIORINIL contains benzalkonium chloride
This medicine contains 0.008 mg of benzalkonium chloride per dose equivalent to 0.1 mg/ml.
Benzalkonium chloride (BAC) contained as a preservative in BIORINIL, especially when used for
long periods, can cause irritation and swelling inside the nose. If you suspect such a reaction
(persistent nasal congestion), a nasal medicine should be used if possible
without BAC. If such nasal medicines without BAC are not available, another pharmaceutical form should be considered.
It may cause bronchospasm. Irritating, it may cause local skin reactions.
3. How to use BIORINIL
Use this medicine following exactly the instructions of your doctor or pharmacist.
If you have any doubts, consult your doctor or pharmacist.
Adults and adolescents over 12 years of age
For nasal spray.
The recommended dose is 1 or 2 sprays per nostril 3 or 4 times a day.
Each spray delivers 0.08 ml of product.
Instructions for use

- 1. Shake the bottle.
- 2. For the first use, to activate the dispenser, press down with your index and middle fingers until a spray is released.
- 3. Spray the product into the nostrils. After use, keep the dispensing nozzle covered with the dust cap.
If you use more BIORINIL than you should
In case of ingestion/accidental intake of an excessive dose of BIORINIL, inform
your doctor immediately or go to the nearest hospital.
The product, if accidentally ingested or if used for a long period at excessive doses,
may cause toxic effects.
Symptoms
In case of accidental ingestion of an excessive dose of Biorinil, you/the child may
experience the undesirable effects caused by general absorption, as reported in paragraph 4.
More rarely, a series of effects affecting the nervous system: psychomotor hyperactivity,
sleep disturbances, anxiety, depression or aggression (particularly in children).
Treatment
In case of ingestion/accidental intake of an excessive dose of Biorinil, the doctor will adopt
the appropriate supportive therapy.
If you forget to use Biorinil
Do not use a double dose to make up for a missed dose.
If you stop using Biorinil
If you have any doubts about the use of this medicine, consult your doctor or pharmacist.
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Local side effects that may occur with Biorinil are as follows:
Effects relating to the site of administration
Sensitization reactions, a feeling of worsening of symptoms due to prolonged use.
General side effects are extremely unlikely both due to the low doses used and the route of
administration; however, their occurrence may be favored by treatments conducted for
prolonged periods of time.
In this case, the absorption of substances that stimulate the sympathetic nervous system
(sympathomimetic) may determine the following general side effects:
Effects relating to the nervous system
Headache, restlessness and insomnia
Effects relating to blood circulation
Arterial hypertension (high blood pressure), alteration of heart rate
Effects relating to the kidney and urinary tract
Disorders in urine emission (urinary disturbances)
General effects with intranasal corticosteroids may occur, particularly if prescribed at
high doses for prolonged periods.
Effects relating to the endocrine system
Cushing's syndrome, alteration of the control mechanisms of the adrenal glands.
Rare frequency; blurred vision.
Reporting of side effects
If you experience any side effects, including those not listed in this leaflet, please
consult your doctor or pharmacist. You can also report side effects directly to
www.agenziafarmaco.gov.it/content/come-segnalare-una-sospetta-reazione-
avversa”.Reporting side effects can help provide more information
on the safety of this medicine.
5. How to store BIORINIL
Do not store at a temperature above 25°C.
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the package after Scad. The
expiry date refers to the last day of that month.
The period of validity after first opening of the bottle is 30 days.
Do not dispose of any medicine in wastewater or household waste. Ask your pharmacist
how to eliminate medicines that you no longer use. This will help protect the environment.
6. Contents of the pack and other information
What Biorinil contains
- are Betamethasone (0.05 g in 100 ml of suspension), Tetrizoline hydrochloride (0.1 g in 100 ml of suspension) The other components are benzalkonium chloride(see paragraph BIORINIL containsbenzalkonium chloride), disodium edetate, polysorbate 60, polysorbate 80, disodium phosphate dodecahydrate, sodium phosphate monobasic dihydrate, sodium chloride, sodium hydroxide (for pH adjustment), purified water.
Description of the appearance of Biorinil and contents of the pack
BIORINIL is a nasal spray, suspension.
It is available in a pack containing 1 bottle of 10 ml (at least 125 doses) for
nasal nebulizations with an automatic dosage spray valve.
Marketing Authorisation Holder and Manufacturer
Marketing Authorisation Holder
THEA FARMA S.p.A.
Via Tiziano, 32
20145 MILANO
Manufacturer
FARMILA-THEA FARMACEUTICI S.p.A.
Via Enrico Fermi, 50
20019 Settimo Milanese (MI)

- Країна реєстрації
- Лікарська формаNasal spray, suspension, 0.05% + 0.1%
- Потрібен рецептНі
- Виробник
- Ця інформація надана лише для ознайомлення і не є медичною порадою. Рішення щодо лікування завжди приймає лікар.
- Альтернативи до BIORINILЛікарська форма: Nasal drops, suspension, 400 MICROGRAMSДіюча речовина: fluticasoneВиробник: GENETIC S.P.A.Рецепт не потрібенЛікарська форма: Nasal spray, suspension, 50 MICROGRAMSДіюча речовина: mometasoneВиробник: D.M.G. ITALIA S.R.L.Рецепт не потрібенЛікарська форма: Nasal spray, suspension, 27,5 MCGДіюча речовина: флутиказона фуроатВиробник: GLAXOSMITHKLINE TRADING SERVICES LIMITEDРецепт не потрібен
Аналоги BIORINIL в інших країнах
Препарати з тією самою діючою речовиною, доступні в інших країнах.
Аналог BIORINIL у Україна
Аналог BIORINIL у Іспанія
Лікарі онлайн щодо BIORINIL
Застосування, безпека та можливість призначення рецепта — за результатами медичної оцінки.
Отримайте рецепт на BIORINIL онлайн
Заповніть форму за 2 хвилини
Розкажіть про симптоми, історію хвороби та потрібний препарат.
Оберіть лікаря або ми призначимо
Оберіть спеціаліста або ми підберемо найближчого доступного лікаря.
Лікар розглядає ваш випадок
Зазвичай протягом 30 хвилин. Може ставити уточнювальні запитання в чаті.
Отримайте в будь-якій аптеці
Електронний рецепт надсилається на вашу пошту — дійсний по всій Польщі.
Часті запитання
BIORINIL не потребує рецепта в Італія. Ви можете обговорити з лікарем онлайн, чи підходить цей лікарський засіб для вашої ситуації.
BIORINIL виробляється компанією THEA FARMA S.P.A.. Назва бренду та упаковка можуть відрізнятися залежно від дистрибʼютора.
Лікарі, зокрема Сімейні лікарі, Психіатри, Дерматологи, Кардіологи, Ендокринологи, Гастроентерологи, Пульмонологи, Нефрологи, Ревматологи, Гематологи, Інфекціоністи, Алергологи, Геріатри, Педіатри, Онкологи, можуть оцінити доцільність застосування BIORINIL з урахуванням вашого стану та місцевих правил. Ви можете записатися на онлайн-консультацію, щоб обговорити симптоми та можливі подальші кроки.
Польща має добре розвинену систему охорони здоров'я у великих містах, таких як Варшава, Краків, Вроцлав і Гданськ. Аптеки широко доступні та працюють відповідно до чинного законодавства, забезпечуючи доступ до рецептурних препаратів.
Ви можете придбати BIORINIL у Варшаві, Кракові, Вроцлаві або Гданську в будь-якій аптеці за наявності дійсного рецепта.
Щоб отримати рецепт, ви можете скористатися Oladoctor:
Інші препарати з тією самою діючою речовиною () включають AKTANOS, ARINIT, AVAMYS. Вони можуть відрізнятися торговою назвою або формою випуску, але містять той самий терапевтичний компонент. Перед зміною або початком прийому нового препарату варто проконсультуватися з лікарем.
















