Інструкція із застосування NEO KROMATON BIKOMPLESSO
Зміст інструкції
- NEO CROMATON BICOMPLESSO 10000
- NEO CROMATON BICOMPLESSO 10000 contains esters of p-hydroxybenzoic acid
- NEO CROMATON BICOMPLESSO 10000 contains less than 1 mmol (23 mg) of sodium per
NEO CROMATON BICOMPLESSO 10000
powder and solvent for oral solution
Cyanocobalamin + calcium folinate + thiamine monophosphate chloride + pyridoxine hydrochloride +
nicotinamide + riboflavin-5-monophosphate sodium salt + dexpanthenol
Read this leaflet carefully before taking this medicine as it contains
important information for you.
Always take this medicine exactly as described in this leaflet or as your
doctor or pharmacist has told you.
- Keep this leaflet. You may need to read it again.
- If you want more information or advice, ask your pharmacist.
- If any side effects occur, including those not listed in this leaflet, tell your doctor or pharmacist. See section 4. Contents of this leaflet:
- 1. What NEO CROMATON BICOMPLESSO 10000 is and what it is used for
- 2. What you need to know before you take NEO CROMATON BICOMPLESSO 10000
- 3. How to take NEO CROMATON BICOMPLESSO 10000
- 4. Possible side effects
- 5. How to store NEO CROMATON BICOMPLESSO 10000
- 6. Contents of the pack and other information
1. WHAT IS NEO CROMATON BICOMPLESSO 10000 AND WHAT IS IT USED FOR
NEO CROMATON BICOMPLESSO 10000 is a multivitamin complex used in
adults and children:
- in the treatment of macrocytic anemia syndromes (conditions caused by an alteration in the maturation of red blood cells) or anemias (pathological reduction of hemoglobin in the blood) due to a specific deficiency, also during pregnancy, puerperium (period immediately following childbirth) and breastfeeding;
- in the treatment of convalescence;
- as an adjuvant (helper) in the therapy of infectious toxic states, in the aftermath of hepatitis (liver inflammation) and in case of hepatic functional deficit (reduction of liver function);
- during antibiotic therapy;
- in the treatment of specific deficiency syndromes (lack of specific elements) caused by malnutrition (deficient nutrition) or inadequate diets.
2. WHAT YOU NEED TO KNOW BEFORE TAKING NEO CROMATON
BICOMPLEX 10000
Do not take NEO CROMATON BICOMPLEX 10000
- if you are allergic to the active ingredients or to any of the other ingredients of this medicine (listed in section 6);
- if you have cancer.
Warnings and precautions
Talk to your doctor or pharmacist before taking NEO CROMATON BICOMPLEX
- 10000.
If you suffer from cancer, the medicine will not be prescribed to you to treat anemia (see “Do not
take NEO CROMATON BICOMPLEX 10000”).
The yellow color that your urine may assume is due to the presence of vitamin
B2.
Children and adolescents
The medicine can be given to children and adolescents (for the dosage see
section 3 “How to take NEO CROMATON BICOMPLEX 10000”).
Other medicines and NEO CROMATON BICOMPLEX 10000
Tell your doctor or pharmacist if you are taking, have recently taken or might
take any other medicines.
The use of NEO CROMATON BICOMPLEX 10000 is not recommended in association with:
- levodopa (medicine used for the treatment of Parkinson's disease, a neurodegenerative disease), as it may counteract the effects of the latter; this does not occur with the carbidopa-levodopa association;
- phenobarbital, phenytoin or primidone because folic acid (contained in the medicine) at high doses can reduce the antiepileptic effect of these drugs by increasing their degradation by the body. If necessary, your doctor will monitor the concentration of these antiepileptic drugs in your blood. A similar relationship is expected with other anticonvulsant drugs including sodium valproate, carbamazepine and barbiturates.
Take care when taking NEO CROMATON BICOMPLEX 10000 with:
- tricyclic antidepressants or phenothiazines (antipsychotics). In this case, your doctor may increase the dose of NEO CROMATON BICOMPLEX 10000.
- probenecid (medicine used to reduce uric acid concentrations in the blood), as it reduces the absorption of NEO CROMATON BICOMPLEX 10000.
- chloramphenicol, cycloserine and penicillamine (antibiotics), ethionamide and isoniazid (drugs used for the treatment of tuberculosis), hydralazine (drug used to lower blood pressure) or immunosuppressants. Concomitant use of these medicines may cause anemia (pathological reduction of hemoglobin in the blood) or peripheral neuritis (inflammation of the nerves). These drugs may counteract the action of NEO CROMATON BICOMPLEX 10000, your doctor may therefore decide to increase the dose;
- estrogens (female sex hormones). In this case, your doctor may decide to increase the dose of NEO CROMATON BICOMPLEX 10000;
- methotrexate (drug used for the treatment of various forms of cancer) and sulfasalazine (drug used in the therapy of long-lasting inflammatory bowel diseases) can decrease the activity of folic acid;
- chloramphenicol, as if administered simultaneously with NEO CROMATON BICOMPLEX 10000, it may block the growth of blood cells induced by some of the active ingredients contained in NEO CROMATON BICOMPLEX 10000.
Also keep in mind that:
- if you are taking Lithium as an antidepressant, folate supplements (contained in NEO CROMATON BICOMPLEX 10000) improve the effects of therapy;
- anesthesia (abolition of pain sensitivity) performed with nitrous oxide may cause an acute folic acid deficiency;
- acetyl-salicylic acid (anti-inflammatory drug) may determine an increase in the elimination of folic acid.
Finally, consider that high doses of riboflavin can determine alterations in the
results of some diagnostic tests:
- measurement of the amount of catecholamines (a group of hormones produced by the adrenal glands) in the urine performed with a fluorometric method, because riboflavin interferes with the production of fluorescent substances falsifying the results;
- appearance of false positives in the determination of urobilinogen values (a substance produced at the intestinal level from bilirubin) with Ehrlich's test (test performed to evaluate psychoactive substances).
NEO CROMATON BICOMPLEX 10000with alcohol
Ethanol (alcohol) can determine an increase in the elimination of folic acid and can alter
intestinal absorption of riboflavin.
Pregnancy and breastfeeding
If you are pregnant, suspect you are pregnant or are planning a pregnancy, or if you are
breastfeeding, ask your doctor or pharmacist for advice before taking this
medicine.
Pregnancy
You can use the medicine during pregnancy, if clinically necessary. No adverse effects have been
documented during pregnancy with the assumption of therapeutic doses of
NEO CROMATON BICOMPLEX 10000.
However, the assumption of high doses of pyridoxine (component of the medicine) during
pregnancy can lead to dependence syndrome in the newborn (a particular form of
withdrawal syndrome, characterized by the appearance of convulsions).
Breastfeeding
The active substances of NEO CROMATON BICOMPLEX 10000 are excreted in breast
milk, but at therapeutic doses it is believed that there are no adverse effects on
newborns/infants. However, consult your doctor or pharmacist before taking this
medicine.
Driving and operating machinery
NEO CROMATON BICOMPLEX 10000 does not alter or negligibly alters the
ability to drive vehicles or operate machinery.
NEO CROMATON BICOMPLEX 10000 contains ethanol, fructose, esters of p-hydroxybenzoic acid and sodium
NEO CROMATON BICOMPLEX 10000 contains 711 mg of alcohol (ethanol)in each
vial which is equivalent to 0.711 g / 15 g. The amount of ethanol contained in a
vial of this medicine is equivalent to less than 18 ml of beer or 8 ml of wine per
vial.
The amount of alcohol in this medicine will not produce significant effects in adults and its
effects in children are not evident. Some effects may occur in small children,
for example feeling sleepy.
NEO CROMATON BICOMPLEX 10000 contains 4 g of fructoseper vial
equivalent to 4 g / 15 g. If your doctor has told you that you (or the child) are
intolerant to some sugars, or if you have a diagnosis of hereditary fructose intolerance, a
rare genetic disease in which patients cannot transform fructose, talk to your
doctor before you (or the child) take this medicine.
NEO CROMATON BICOMPLESSO 10000 contains esters of p-hydroxybenzoic acid
which may cause allergic reactions (even delayed ones).
NEO CROMATON BICOMPLESSO 10000 contains less than 1 mmol (23 mg) of sodium per
vial, meaning it is essentially “sodium-free”.
3. HOW TO TAKE NEO CROMATON BICOMPLESSO 10000
Take this medicine following exactly as indicated in this leaflet or as instructed by your doctor or pharmacist. If you have any doubts, consult your doctor or pharmacist.
Unscrew the cap and take the preparation (see the figure below).
MODE OF USE
- 1) Screw the cap on completely 2) Observe that the membrane of

colored until it stops by holding the vial in a vertical position. The resistance you feel when screwing on the cap is due to the breaking of the membrane which, with its particular thickness, guarantees the separation between the powder contained in the cap and the liquid below. The "key", attached to the package, if inserted on the cap of the vial facilitates its screwing and unscrewing.
separation opens.
- 3) Shake the vial repeatedly

and vigorously for at least 15
seconds to allow the
powder to dissolve in the liquid
below.
- 4) Unscrew the cap and take the


medicine either directly from the
vial thus obtained as is
or diluted with water,
milk, fruit juices or
other beverages. In the latter
case, shake the vial to
facilitate emptying. In some rare cases, the closing disc may detach and fall into the liquid. If this happens, even though it is made of harmless material, remove it from the glass before taking it. The containers of this
specialty are rigorously controlled according to law.
Adults
The recommended dose is two vials per day, before main meals, or as
directed by your doctor.
Use in children
The recommended dose is one vial per day or as directed by your doctor.
Once the powder in the cap is dissolved in the liquid below, it is necessary to take the
preparation immediately or in any case within 24 hours.
If you take more NEO CROMATON BICOMPLESSO 10000 than you should
No cases of overdose have been reported.
In case of accidental ingestion/intake of an excessive dose of NEO CROMATON
BICOMPLESSO 10000, immediately inform your doctor or go to the nearest hospital.
If you have any doubts about the use of this medicine, ask your doctor or pharmacist.
4. POSSIBLE SIDE EFFECTS
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Side effects with frequency not known (frequency cannot be estimated from available data):
- allergic reactions, including erythema (skin irritation), rash (sudden redness of the skin), itching, urticaria (skin lesion characterised by the appearance of a more or less itchy rash), dyspnea (difficulty breathing);
- anxiety, confusion, sleep disorders;
- dizziness, headache, peripheral neuropathies (after administration of high doses for long periods of time);
- anorexia (loss of appetite), nausea, abdominal distension and flatulence (bloating).
- malaise, irritability.
Reporting of side effects
If you get any side effects, talk to your doctor or pharmacist. You can also report side effects directly
through the national reporting system
at http://www.aifa.gov.it/content/segnalazioni-reazioni-avverse .
By reporting side effects you can help provide more information on the
safety of this medicine.
5. HOW TO STORE NEO CROMATON BICOMPLESSO 10000
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the packaging. The expiry
date refers to the last day of that month and the product in intact packaging,
correctly stored.
This medicine does not require any particular storage conditions.
Once the powder from the cap has been dissolved in the liquid below, it is necessary to take the
preparation immediately or in any case within 24 hours.
Do not dispose of any medicine in wastewater or household waste. Ask your pharmacist
how to dispose of medicines you no longer use. This will help protect the environment.
6. PACKAGE CONTENTS AND OTHER INFORMATION
What NEO CROMATON BICOMPLESSO 10000 contains
Each reservoir cap contains:
Active ingredients: cyanocobalamin 750 micrograms, calcium folinate 400 micrograms.
Other ingredients: rice starch, pregelatinized corn starch, sodium starch glycolate, colloidal
anhydrous silica, magnesium stearate.
Each vial contains:
Active ingredients: thiamine monophosphate chloride 20 mg, pyridoxine hydrochloride 4 mg, nicotinamide
40 mg, riboflavin-5'-monophosphate sodium salt 4 mg, dexpanthenol 30 mg.
Other ingredients: fructose, glycerol, esters of p-hydroxybenzoic acid, blueberry aroma,
95° ethanol, purified water, citric acid.
Description of the appearance of NEO CROMATON BICOMPLESSO 10000 and contents of the
package
Powder and solvent for oral solution.
The package contains 10 vials with reservoir cap housed in cardboard boxes.
The vials contain an extemporaneous syrup (prepared at the time of use) and are
closed with a reservoir cap.
Marketing Authorisation Holder
- A. Menarini Industrie Farmaceutiche Riunite s.r.l., via Sette Santi, 3 - Florence.
Manufacturer
Laboratorios Menarini S.A., Badalona (Barcelona) - Alfonso XII 587 – Spain.
- A. Menarini Manufacturing Logistics and Services s.r.l. , Via Sette Santi 3 – Florence.

- Країна реєстрації
- Лікарська формаPowder and solvent for oral solution
- Потрібен рецептНі
- Виробник
- Ця інформація надана лише для ознайомлення і не є медичною порадою. Рішення щодо лікування завжди приймає лікар.
- Альтернативи до NEO KROMATON BIKOMPLESSOЛікарська форма: Soft capsule, 1 MICROGRAMДіюча речовина: Альфа-кальцидолВиробник: DOC GENERICI SRLПотрібен рецептЛікарська форма: Soft capsule, 0.25 microgramsДіюча речовина: Альфа-кальцидолВиробник: ZENTIVA ITALIA S.R.L.Потрібен рецептЛікарська форма: Soft capsule, 0.25 MCGДіюча речовина: Альфа-кальцидолВиробник: THERAMEX IRELAND LIMITEDПотрібен рецепт
Аналоги NEO KROMATON BIKOMPLESSO в інших країнах
Препарати з тією самою діючою речовиною, доступні в інших країнах.
Аналог NEO KROMATON BIKOMPLESSO у Польща
Аналог NEO KROMATON BIKOMPLESSO у Україна
Лікарі онлайн щодо NEO KROMATON BIKOMPLESSO
Застосування, безпека та можливість призначення рецепта — за результатами медичної оцінки.
Отримайте рецепт на NEO KROMATON BIKOMPLESSO онлайн
Заповніть форму за 2 хвилини
Розкажіть про симптоми, історію хвороби та потрібний препарат.
Оберіть лікаря або ми призначимо
Оберіть спеціаліста або ми підберемо найближчого доступного лікаря.
Лікар розглядає ваш випадок
Зазвичай протягом 30 хвилин. Може ставити уточнювальні запитання в чаті.
Отримайте в будь-якій аптеці
Електронний рецепт надсилається на вашу пошту — дійсний по всій Польщі.
Часті запитання
NEO KROMATON BIKOMPLESSO не потребує рецепта в Італія. Ви можете обговорити з лікарем онлайн, чи підходить цей лікарський засіб для вашої ситуації.
NEO KROMATON BIKOMPLESSO виробляється компанією A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L.. Назва бренду та упаковка можуть відрізнятися залежно від дистрибʼютора.
Лікарі, зокрема Сімейні лікарі, Психіатри, Дерматологи, Кардіологи, Ендокринологи, Гастроентерологи, Пульмонологи, Нефрологи, Ревматологи, Гематологи, Інфекціоністи, Алергологи, Геріатри, Педіатри, Онкологи, можуть оцінити доцільність застосування NEO KROMATON BIKOMPLESSO з урахуванням вашого стану та місцевих правил. Ви можете записатися на онлайн-консультацію, щоб обговорити симптоми та можливі подальші кроки.
Польща має добре розвинену систему охорони здоров'я у великих містах, таких як Варшава, Краків, Вроцлав і Гданськ. Аптеки широко доступні та працюють відповідно до чинного законодавства, забезпечуючи доступ до рецептурних препаратів.
Ви можете придбати NEO KROMATON BIKOMPLESSO у Варшаві, Кракові, Вроцлаві або Гданську в будь-якій аптеці за наявності дійсного рецепта.
Щоб отримати рецепт, ви можете скористатися Oladoctor:
Інші препарати з тією самою діючою речовиною () включають ALFAKALKIDOLO DOK, ALFAKALKIDOLO TSENTIVA, ALPA D3. Вони можуть відрізнятися торговою назвою або формою випуску, але містять той самий терапевтичний компонент. Перед зміною або початком прийому нового препарату варто проконсультуватися з лікарем.
















