Інструкція із застосування METADOXIL
Зміст інструкції
METADOXIL 500 mg tablets, 500 mg/15 ml oral solution
Metadoxina
Read this leaflet carefully before taking this medicine as it contains important information for you.
- Keep this leaflet. You may need to read it again.
- If you have any questions, ask your doctor or pharmacist.
- This medicine has been prescribed for you only. Do not pass it on to others, even if they have the same symptoms as you, as it may be harmful.
- If you get any side effects, even those not listed in this leaflet, tell your doctor or pharmacist. See section 4.
Contents of this leaflet:
- 1. What METADOXIL is and what it is used for
- 2. What you need to know before you take METADOXIL
- 3. How to take METADOXIL
- 4. Possible side effects
- 5. How to store METADOXIL
- 6. Contents of the pack and other information
1. What is METADOXIL and what is it used for
METADOXIL contains the active ingredient metadoxine, used in alcohol intoxication. This
medicinal product works by reducing blood alcohol levels (blood alcohol concentration) and facilitating its elimination
with urine.
This medicine is indicated in the long-term condition caused by habitual and
prolonged use of alcoholic beverages (chronic alcoholism).
In case of acute alcohol intoxication (acute alcoholism) METADOXIL 300 mg/5 ml
injectable solution is indicated.
2. What you need to know before taking METADOXIL
Do not take METADOXIL
- if you are allergic to metadoxine or any of the other ingredients of this medicine (listed in section 6);
- if you are breastfeeding (see section “Pregnancy and breastfeeding”).
Warnings and precautions
Talk to your doctor or pharmacist before taking METADOXIL.
Take this medicine with caution and inform your doctor if you suffer from Parkinson's disease and are being
treated with levodopa, because metadoxine may reduce its effects (see section “Other
medicines and METADOXIL”).
Children and adolescents
This medicine is not recommended for children and adolescents.
Other medicines and METADOXIL
Tell your doctor or pharmacist if you are taking, have recently taken or might take
any other medicines.
Take this medicine with caution and inform your doctor if you are taking levodopa, used for the
treatment of Parkinson's disease, as metadoxine may reduce its effects.
Pregnancy and breastfeeding
If you are pregnant, suspect you are pregnant or are planning to become pregnant, or if you are breastfeeding
with breast milk, ask your doctor or pharmacist for advice before taking this medicine.
METADOXIL is not recommended during pregnancy, except in cases of absolute necessity and under the direct
supervision of a doctor.
Do not take METADOXIL if you are breastfeeding because metadoxine reduces the levels of a hormone,
called prolactin, in the blood (hypoprolactinemic action) (see section “Do not take
METADOXIL”).
Driving and operating machinery
METADOXIL does not impair the ability to drive vehicles and operate machinery.
METADOXIL 500 mg / 15 ml oral solution contains sucrose and methyl para-hydroxybenzoate
This medicine contains sucrose, a type of sugar. If your doctor has diagnosed
an intolerance to certain sugars, contact him before taking this medicine. In particular, each
bottle contains 7.5 g of sucrose. This should be taken into consideration in people affected by diabetes
mellitus. It may be harmful to your teeth.
METADOXIL 500 mg / 15 ml oral solution contains methyl para-hydroxybenzoate which may cause
allergic reactions (including delayed reactions).
3. How to take METADOXIL
Take this medicine following exactly the instructions of your doctor or pharmacist. If you
have any doubts, consult your doctor or pharmacist.
METADOXIL 500 mg tablets
The recommended dose is 2 tablets per day to be taken orally (by mouth) in the treatment
of chronic conditions.
METADOXIL 500 mg/15 ml oral solution
The recommended dose is 2 vials per day to be taken orally (by mouth) in the treatment
of chronic conditions.
If you take more METADOXIL than you should
No cases of overdose of this medicine are known.
In case of accidental intake/ingestion of an excessive dose of METADOXIL, immediately
inform your doctor or go to the nearest hospital.
If you forget to take METADOXIL
Do not take a double dose to make up for a missed dose.
If you have any doubts about the use of this medicine, consult your doctor or pharmacist.
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
The following side effects may occur:
Very rare(may affect up to 1 in 10,000 people)
- allergic reactions (hypersensitivity);
- numbness, tingling, altered sensation and weakness in the arms and legs (peripheral neuropathy). These symptoms occur especially if you take the medicine for a long time and tend to disappear after stopping treatment;
- dizziness, disorientation;
- diarrhoea, vomiting;
- swelling of the face, lips, mouth, tongue or throat that can cause difficulty swallowing and breathing (angioedema), skin irritation (rash, urticaria), itching;
- loss of appetite.
In some cases, it may be difficult to distinguish side effects from the symptoms of the underlying disease.
Reporting of side effects
If you get any side effects, even those not listed in this leaflet, tell your
doctor or pharmacist. You can also report side effects directly through the
national reporting system at www.agenziafarmaco.gov.it/it/responsabili .
By reporting side effects you can help provide more information on the safety
of this medicine.
5. How to store METADOXIL
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the packaging after “Exp.”. The
expiry date refers to the last day of that month.
Store at a temperature not exceeding 30°C and protect from light.
Do not dispose of any medicine in waste water or household waste. Ask your pharmacist how to
dispose of medicines you no longer use. This will help protect the environment.
6. Package Contents and Other Information
What METADOXIL contains
METADOXIL 500 mg tablets
- The active ingredient is metadoxine. Each tablet contains 500 mg of metadoxine.
- The other ingredients are: microcrystalline cellulose, magnesium stearate.
METADOXIL500 mg/15 ml oral solution
- The active ingredient is metadoxine. Each 15 ml vial contains 500 mg of metadoxine.
- The other ingredients are: sucrose, sorbic acid, sodium edetate, methyl parahydroxybenzoate, mandarin aroma, purified water.
Description of the appearance of METADOXIL and package contents
METADOXIL 500 mg tablets
Pack of 30 tablets.
METADOXIL500 mg/15 ml oral solution
Pack of 10 vials of 15 ml.
Marketing Authorisation Holder and Manufacturer
Laboratori Baldacci S.p.A. – Via S. Michele degli Scalzi 73 – 56124 Pisa – Italy
METADOXIL 300 mg/5 ml injectable solution
Metadoxine
Read this leaflet carefully before you start using this medicine as it contains
important information for you.
- Keep this leaflet. You may need to read it again.
- If you have any questions, ask your doctor, pharmacist or nurse.
- This medicine has been prescribed for you only. Do not pass it on to others, even if their symptoms are the same as yours, as it could be harmful.
- If you get any side effects, even those not listed in this leaflet, tell your doctor, pharmacist or nurse. See section 4.
Contents of this leaflet:
- 1. What METADOXIL is and what it is used for
- 2. What you need to know before you use METADOXIL
- 3. How to use METADOXIL
- 4. Possible side effects
- 5. How to store METADOXIL
- 6. Contents of the pack and other information
1. What METADOXIL is and what it is used for
METADOXIL contains the active ingredient metadoxine, used in alcohol poisoning.
This medicine works by reducing alcohol levels in the blood (blood alcohol concentration) and
facilitating its elimination with urine.
This medicine is indicated in case of acute alcohol poisoning (acute alcoholism) and in the
long-lasting condition caused by habitual and prolonged use of alcoholic beverages
(chronic alcoholism).
2. What you need to know before you use METADOXIL
Do not use METADOXIL
- if you are allergic to metadoxine or any of the other ingredients of this medicine (listed in section 6);
- if you are breastfeeding (see section “Pregnancy and breastfeeding”).
Warnings and precautions
Consult your doctor or pharmacist before using METADOXIL.
Use this medicine with caution and inform your doctor if you suffer from Parkinson's disease and are
being treated with levodopa, because metadoxine may reduce its effects (see section
“Other medicines and METADOXIL”).
Children and adolescents
The use of METADOXIL is not recommended in children and adolescents.
Other medicines and METADOXIL
Tell your doctor or pharmacist if you are taking, have recently taken or might take
any other medicines. Use this medicine with caution and inform your doctor if you are
taking levodopa, used for the treatment of Parkinson's disease, as metadoxine
may reduce its effects.
Pregnancy, breastfeeding and fertility
If you are pregnant, suspect you are pregnant or are planning a pregnancy, or if you are
breastfeeding, ask your doctor or pharmacist for advice before using this medicine.
The use of METADOXIL is not recommended during pregnancy, except in cases of absolute
necessity and under the direct control of the doctor.
Do not use METADOXIL if you are breastfeeding because metadoxine reduces the levels of a
hormone, called prolactin, in the blood (hypoprolactinemic action) (see section
“Do not use METADOXIL”).
Driving and using machines
The use of METADOXIL does not alter the ability to drive vehicles and operate machinery.
METADOXIL contains sodium metabisulfite and methyl parahydroxybenzoate
This medicine contains sodium metabisulfite, which rarely may cause serious hypersensitivity reactions and bronchospasm.
METADOXIL contains methyl parahydroxybenzoate which may cause allergic reactions
(including delayed reactions) and, exceptionally, bronchospasm.
3. How to use METADOXIL
Use this medicine following the instructions of your doctor, pharmacist or
nurse exactly. If you have any doubts, consult your doctor, pharmacist or nurse.
This medicine must be administered via an injection into a muscle (intramuscular route) or into a vein (intravenous route).
Treatment of acute alcohol poisoning
The recommended dose is 1-2 vials via intramuscular or intravenous route.
Treatment of chronic alcohol poisoning
The recommended dose is 1 vial per day via intramuscular or intravenous route.
If you use more METADOXIL than you should
No cases of overdose of this medicine are known.
In case of accidental ingestion/administration of an excessive dose of METADOXIL, immediately notify your doctor or go to the nearest hospital.
If you forget to use METADOXIL
Do not use a double dose to make up for a missed dose.
If you have any doubts about the use of this medicine, consult your doctor, pharmacist or
nurse.
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
The following side effects may occur:
Very rare(may affect up to 1 in 10,000 people)
- allergic reactions (hypersensitivity);
- numbness, tingling, altered sensation and weakness in the arms and legs (peripheral neuropathy). These symptoms occur especially if you take the medicine for a long time and tend to disappear after stopping treatment;
- dizziness, disorientation;
- diarrhoea, vomiting;
- swelling of the face, lips, mouth, tongue or throat that can cause difficulty swallowing and breathing (angioedema), skin irritation (rash, urticaria), itching;
- loss of appetite.
In some cases, it may be difficult to distinguish side effects from the symptoms of the underlying
disease.
Reporting of side effects
If you get any side effect, even if not listed in this leaflet, please tell your doctor or pharmacist. You can also report side effects directly
through the national reporting system at
www.agenziafarmaco.gov.it/it/responsabili . By reporting side effects you can
help to provide more information on the safety of this medicine.
5. How to store METADOXIL
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the packaging after “EXP.”.
The expiry date refers to the last day of that month.
Store at a temperature not exceeding 30°C and protect from light.
Do not dispose of any medicine in waste water or household waste. Ask your pharmacist
how to dispose of medicines you no longer use. This will help protect the environment.
6. Contents of the pack and other information
WhatMETADOXILcontains
- The active ingredient is metadoxine. Each vial (5 ml) contains 300 mg of metadoxine.
- The other ingredients are: sodium metabisulfite, sodium edetate, methyl p-hydroxybenzoate, water for injections.
Description of the appearance of METADOXIL and contents of the pack
Pack of 10 vials of 5 ml.
Marketing Authorisation Holder
Laboratori Baldacci S.p.A. – Via S. Michele degli Scalzi 73 – 56124 Pisa – Italy
Manufacturer
Doppel Farmaceutici S.r.l. – Via Volturno, 48 – Quinto dè Stampi, Rozzano (MI) – Italy

- Країна реєстрації
- Лікарська формаTablet, 500 MG
- Потрібен рецептТак
- Виробник
- Ця інформація надана лише для ознайомлення і не є медичною порадою. Рішення щодо лікування завжди приймає лікар.
- Альтернативи до METADOXILЛікарська форма: Oral solution, 175 MG/MLДіюча речовина: Drugs used in alcohol dependenceВиробник: LABORATORIO FARMACEUTICO C.T. S.R.L.Потрібен рецептЛікарська форма: Effervescent tablet, 400 MGДіюча речовина: ДисульфирамВиробник: AUROBINDO PHARMA (ITALIA) S.R.L.Потрібен рецептЛікарська форма: Oral solution, 100 MG/20 MLДіюча речовина: naltrexoneВиробник: ZAMBON ITALIA S.R.L.Потрібен рецепт
Аналоги METADOXIL в інших країнах
Препарати з тією самою діючою речовиною, доступні в інших країнах.
Аналог METADOXIL у Україна
Аналог METADOXIL у Іспанія
Лікарі онлайн щодо METADOXIL
Застосування, безпека та можливість призначення рецепта — за результатами медичної оцінки.
Отримайте рецепт на METADOXIL онлайн
Заповніть форму за 2 хвилини
Розкажіть про симптоми, історію хвороби та потрібний препарат.
Оберіть лікаря або ми призначимо
Оберіть спеціаліста або ми підберемо найближчого доступного лікаря.
Лікар розглядає ваш випадок
Зазвичай протягом 30 хвилин. Може ставити уточнювальні запитання в чаті.
Отримайте в будь-якій аптеці
Електронний рецепт надсилається на вашу пошту — дійсний по всій Польщі.
Часті запитання
METADOXIL потребує рецепта в Італія. Ви можете обговорити з лікарем онлайн, чи підходить цей лікарський засіб для вашої ситуації.
METADOXIL виробляється компанією LABORATORI BALDACCI S.P.A.. Назва бренду та упаковка можуть відрізнятися залежно від дистрибʼютора.
Лікарі, зокрема Сімейні лікарі, Психіатри, Дерматологи, Кардіологи, Ендокринологи, Гастроентерологи, Пульмонологи, Нефрологи, Ревматологи, Гематологи, Інфекціоністи, Алергологи, Геріатри, Педіатри, Онкологи, можуть оцінити доцільність застосування METADOXIL з урахуванням вашого стану та місцевих правил. Ви можете записатися на онлайн-консультацію, щоб обговорити симптоми та можливі подальші кроки.
Польща має добре розвинену систему охорони здоров'я у великих містах, таких як Варшава, Краків, Вроцлав і Гданськ. Аптеки широко доступні та працюють відповідно до чинного законодавства, забезпечуючи доступ до рецептурних препаратів.
Ви можете придбати METADOXIL у Варшаві, Кракові, Вроцлаві або Гданську в будь-якій аптеці за наявності дійсного рецепта.
Щоб отримати рецепт, ви можете скористатися Oladoctor:
Інші препарати з тією самою діючою речовиною () включають ALKOVER, ANTABUSE DISPERJETTES, ANTAXONE. Вони можуть відрізнятися торговою назвою або формою випуску, але містять той самий терапевтичний компонент. Перед зміною або початком прийому нового препарату варто проконсультуватися з лікарем.
















