Инструкция по применению EPARGRISEOVIT
Содержание инструкции
EPARGRISEOVIT adults 2500 mcg + 0.70 mg + 12 mg + 150 mg injectable solution, children 1250 mcg + 0.35 mg + 6 mg + 75 mg injectable solution
cyanocobalamin, folic acid, nicotinamide, ascorbic acid
Read this leaflet carefully before you start to take this medicine as it contains important
information for you.
- Keep this leaflet. You may need to read it again.
- If you have any questions, ask your doctor or pharmacist.
- This medicine has been prescribed for you only. Do not pass it on to others, even if their symptoms are the same as yours because it could be harmful.
- If you get any side effects, even those not listed in this leaflet, tell your doctor or pharmacist. See section 4.
Contents of this leaflet:
- 1. What Epargriseovit is and what it is used for
- 2. What you need to know before you take Epargriseovit
- 3. How to take Epargriseovit
- 4. Possible side effects
- 5. How to store Epargriseovit
- 6. Contents of the pack and other information
1. What Epargriseovit is and what it is used for
Epargriseovit contains the active ingredients: cyanocobalamin (vitamin B12), folic acid (vitamin B9),
nicotinamide (vitamin PP) and ascorbic acid (vitamin C).
This medicine is used for the treatment of:
- vitamin deficiencies, especially of vitamin B12 and folic acid, which can occur:
- in severe forms of weakening of the body
- due to insufficient and inadequate nutrition during an illness (malnutrition)
- in the recovery phase of an illness
- in any other condition that requires a supply of vitamins via injection into a vein
- anaemias that respond to the administration of vitamin B12 and folic acid, such as anaemias caused by:
- inadequate diet
- insufficient absorption of vitamins in the intestine
- chronic abuse of alcoholic beverages (alcoholism)
- liver diseases
- pregnancy
- a disease that causes chronic inflammation and, over time, deformation of the joints (rheumatoid arthritis)
- diseases in which medicines against convulsions, malaria, infections and tumours are used
- trigeminal neuralgia
- diseases that cause inflammation or degeneration of the nerves (neuritis) and that respond to the administration of vitamin B12 and folic acid.
How Epargriseovit works
Epargriseovit is a combination of cyanocobalamin, folic acid, nicotinamide and ascorbic acid.
Cyanocobalamin (vitamin B12) is essential for the normal growth of your body, for the
formation of all blood cells (red blood cells, white blood cells, platelets), for the formation of the
cells that line your oral cavity, your stomach, your intestine (gastrointestinal tract), your nasal cavities, your bronchi and your lungs (respiratory tract) and for the normal development of nerve cells.
Folic acid (vitamin B9) is necessary for the normal performance of some important functions of
cyanocobalamin.
Nicotinamide (vitamin PP) is essential for some functions of your metabolism.
Ascorbic acid (vitamin C) is essential for the development of your cartilage and bones, your
teeth and for wound healing. It is also important for the formation of red blood cells and for the
functioning of your immune system.
2. What you need to know before taking Epargriseovit
Do not take Epargriseovit
If you or your child are allergic to any of the active ingredients: cyanocobalamin, folic acid, nicotinamide,
ascorbic acid, or to any of the other ingredients of this medicine (listed in section 6).
Warnings and precautions
Talk to your doctor or pharmacist beforetaking Epargriseovit.
If you or your child suffer from or have ever suffered from any of the following conditions, inform your doctor:
- Anemia, because not all forms of anemia benefit from or can be treated with the vitamins contained in this medicine. The doctor will assess your health status and may decide to have you or your child undergo some tests before prescribing this medicine. The doctor will tell you how often these tests should be performed.
- Pernicious anemia. If you or your child suffer from a form of anemia called pernicious anemia, your doctor may consider it necessary to add another vitamin B to the therapy in addition to that contained in this medicine. The doctor will decide to add another vitamin B based on the results of the tests that you or your child have undergone.
Epargriseovit contains sodium hydrosulfite
Epargriseovit contains a substance called sodium hydrosulfite which rarely can cause serious reactions of
hypersensitivity and bronchospasm.
If you or your child have been diagnosed with asthma, allergy or any form of hypersensitivity, consult your
doctor before taking this medicine.
Epargriseovit may turn urine red. This is normal during treatment with this medicine and
should not be considered abnormal.
Other medicines and Epargriseovit
Tell your doctor or pharmacist if you or your child are taking, have recently taken or
might take any other medicines.
Currently, no medicines are known that cannot be taken together with Epargriseovit.
Pregnancy, breastfeeding and fertility
If you are pregnant, suspect you are pregnant, are planning to become pregnant, or are breastfeeding, ask your
doctor or pharmacist for advice before using this medicine.
Currently, no adverse effects are known following the administration of Epargriseovit during
pregnancy or breastfeeding.
Driving and operating machinery
Epargriseovit does not impair the ability to drive or operate machinery. If you have any doubts, consult your
doctor or pharmacist.
Epargriseovit contains sodium
This medicine contains less than 1 mmol (23 mg) of sodium per dose, i.e. it is practically sodium-free.
3. How to use Epargriseovit
Take this medicine following the instructions of your doctor exactly. If you have any doubts, consult your
doctor or pharmacist.
Your doctor or the doctor caring for your child will determine whether Epargriseovit can be administered
by injection into a vein in the arm (intravenous route) or into a muscle, usually a
buttock (intramuscular route).
The recommended dose in adults is 2-3 doses per week of “Epargriseovit adults”. The doctor will decide whether
you need to take 1 or 2 doses per day.
Use in children
The recommended dose in children is 2-3 doses per week of “Epargriseovit children”, according to the
doctor's judgement.
Instructions for use
Epargriseovit contains two types of vials: vials containing a red liquid and vials containing a liquid
that is colorless. At the time of use, the contents of both vials must be aspirated into the same syringe.
To open, hold the vial vertically, ensuring that the colored point is in the position indicated in the
figure.
Push back the top of the vial as indicated in the figure

If you use more Epargriseovit than you should
In case of administration of an excessive amount of Epargriseovit, no toxic effects of this medicine are known at present. If you have any doubts, consult your doctor or pharmacist.
If you forget to use Epargriseovit
If you forget a dose of Epargriseovit, it can be administered to you or your child as soon as you remember. Epargriseovit can be administered at any time of the day. Do not
use a double dose to make up for a missed dose.
If you stop using Epargriseovit
If you want to stop treatment with Epargriseovit, consult your doctor or pharmacist. There are no
particular recommendations for stopping treatment with Epargriseovit.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Contact your doctor immediatelyif, after administration of Epargriseovit, you experience the following
side effect as it may be serious:
- severe allergic reaction with rapid onset that can lead to death (anaphylactic shock).
The following side effects have been reported in patients treated with Epargriseovit. If any of these side
effects gets worse, or if you notice any side effect not listed in this leaflet, contact your doctor or pharmacist:
- reduction of muscle strength (asthenia);
- fever;
- low blood pressure;
- increased breathing rate (tachypnea);
- skin rashes;
- itching;
- redness, swelling and pain at the injection site.
Reporting of side effects
If you get any side effects, even those not listed in this leaflet, tell your doctor or pharmacist. You can also
report side effects directly through the national reporting system at: http://www.agenziafarmaco.gov.it/it/responsabili .
By reporting side effects you can help provide more information on the safety of this medicine.
5. How to store Epargriseovit
Keep this medicine out of sight and reach of children.
Do not use this medicine after the expiry date which is stated on the pack and the vial after “Exp.”. The
expiry date refers to the last day of that month.
Do not store at a temperature above 25°C.
Do not dispose of any medicine in waste water or household waste. Ask your pharmacist how to dispose of
medicines you no longer use. This will help protect the environment.
6. Contents of the pack and other information
What Epargriseovit contains
The active ingredients of Epargriseovit are cyanocobalamin, folic acid, nicotinamide and ascorbic acid.
Epargriseovit adults contains:
- Vial I (red): 2500 mcg of cyanocobalamin, 0.70 mg of folic acid, 12 mg of nicotinamide;
- Vial II (colourless): 150 mg of ascorbic acid. Epargriseovit children contains:
- Vial I (red): 1250 mcg of cyanocobalamin, 0.35 mg of folic acid, 6 mg of nicotinamide;
- Vial II (colourless): 75 mg of ascorbic acid The other ingredients of Epargriseovit adults are:
- Vial I (red): sodium tartrate, tartaric acid, sodium hydroxide, water for injections;
- Vial II (colourless): sodium hydrosulfite, sodium bicarbonate, water for injections. The other ingredients of Epargriseovit children are:
- Vial I (red): sodium tartrate, tartaric acid, sodium hydroxide, water for injections;
- Vial II (colourless): sodium hydrosulfite, sodium bicarbonate, water for injections.
Description of the appearance of Epargriseovit and contents of the pack
Glass vials I (red) and II (colourless) of 1 ml and 1.5 ml;
- Epargriseovit adults: pack containing 6 vials I of 1 ml and 6 vials II of 1.5 ml;
- Epargriseovit children: pack containing 6 vials I of 1 ml and 6 vials II of 1 ml.
Marketing Authorisation Holder and Manufacturer
Marketing Authorisation Holder
Pfizer Italia S.r.l.
Via Isonzo, 71
04100 Latina
Manufacturer
Actavis Italy S.p.a.
Viale Pasteur 10
20014 Nerviano (MI).

- Страна регистрации
- Форма выпускаInjectable solution, 1 ML + 1,5 ML
- Отпускается по рецептуДа
- Производитель
- Информация на этой странице носит справочный характер и не является медицинской консультацией. Перед началом приема лекарства обязательно проконсультируйтесь с врачом.
- Аналоги EPARGRISEOVITФорма выпуска: Soft capsule, 1 MICROGRAMДействующее вещество: Альфа-кальцидолПроизводитель: DOC GENERICI SRLОтпускается по рецептуФорма выпуска: Soft capsule, 0.25 microgramsДействующее вещество: Альфа-кальцидолПроизводитель: ZENTIVA ITALIA S.R.L.Отпускается по рецептуФорма выпуска: Soft capsule, 0.25 MCGДействующее вещество: Альфа-кальцидолПроизводитель: THERAMEX IRELAND LIMITEDОтпускается по рецепту
Аналоги EPARGRISEOVIT в других странах
Лекарства с тем же действующим веществом, доступные в других странах.
Аналог EPARGRISEOVIT в Польша
Аналог EPARGRISEOVIT в Украина
Аналог EPARGRISEOVIT в Испания
Врачи онлайн по EPARGRISEOVIT
Обсудите применение EPARGRISEOVIT и возможные следующие шаги — по оценке врача.
Получите рецепт на EPARGRISEOVIT онлайн
Заполните форму за 2 минуты
Расскажите о симптомах, истории болезни и нужном препарате.
Выберите врача или мы назначим
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Обычно в течение 30 минут. Может задать уточняющие вопросы в чате.
Получите в любой аптеке
Электронный рецепт отправляется на вашу почту — действителен по всей Польше.
Часто задаваемые вопросы
EPARGRISEOVIT требует рецепта в Италия. Вы можете уточнить у врача онлайн, подходит ли это лекарство для вашей ситуации.
EPARGRISEOVIT производится компанией PFIZER ITALIA S.R.L.. Упаковка и торговое название могут отличаться в зависимости от дистрибьютора.
Врачи, включая Семейные врачи, Психиатры, Дерматологи, Кардиологи, Эндокринологи, Гастроэнтерологи, Пульмонологи, Нефрологи, Ревматологи, Гематологи, Инфекционисты, Аллергологи, Гериатры, Педиатры, Онкологи, могут оценить целесообразность применения EPARGRISEOVIT с учетом вашей ситуации и местных правил. Вы можете записаться на онлайн-консультацию, чтобы обсудить возможные варианты.
Польша имеет хорошо развитую систему здравоохранения в крупных городах, таких как Варшава, Краков, Вроцлав и Гданьск. Аптеки широко доступны и работают в соответствии с действующим законодательством, обеспечивая доступ к рецептурным препаратам.
Вы можете купить EPARGRISEOVIT в Варшаве, Кракове, Вроцлаве или Гданьске в любой аптеке при наличии действующего рецепта.
Чтобы получить рецепт, вы можете воспользоваться Oladoctor:
Другие лекарства с тем же действующим веществом () включают ALFAKALKIDOLO DOK, ALFAKALKIDOLO TSENTIVA, ALPA D3. Они могут отличаться торговым названием или формой выпуска, но содержат одинаковый терапевтический компонент. Перед изменением лечения рекомендуется проконсультироваться с врачом.
















