КОННЕТТИВИНА 0.2% Крем

Содержание инструкции

1. Connettivina 2 mg/ ml Cutaneous Spray, solution
   1. What Connettivina is and what it is used for
   2. What you need to know before using Connettivina
   3. How to use Connettivina
   4. Possible side effects
   5. How to store Connettivina
   6. Contents of the pack and other information
2. Connettivina 2 mg impregnated gauzes, 4 mg impregnated gauzes, 12 mg impregnated gauzes
   1. What Connettivina is and what it is used for
   2. What you need to know before using Connettivina
   3. How to use Connettivina
   4. Possible side effects
   5. How to store Connettivina
   6. Package contents and other information
3. Connettivina 2 mg/g gel
   1. What is Connettivina and what is it used for
   2. What you need to know before using Connettivina
   3. How to use Connettivina
   4. Possible side effects
   5. How to store Connettivina
   6. Package Contents and Other Information
4. Connettivina 2 mg/g cream
   1. What is Connettivina and what is it used for
   2. What you need to know before using Connettivina
   3. How to use Connettivina
   4. Possible side effects
   5. How to store Connettivina
   6. Contents of the pack and other information

Connettivina 2 mg/ ml Cutaneous Spray, solution

Sodium hyaluronate

Read this leaflet carefully before using this medicine as it contains important
information for you.
Always use this medicine exactly as described in this leaflet or as your doctor or pharmacist has told you.

• Keep this leaflet. You may need to read it again.
• If you want more information or advice, ask your pharmacist.
• If any side effects occur, including those not listed in this leaflet, tell your doctor or pharmacist. See section 4.
• See a doctor if you do not feel better or if your symptoms get worse after a short period of treatment.

Contents of this leaflet:

• 1. What Connettivina is and what it is used for
• 2. What you need to know before using Connettivina
• 3. How to use Connettivina
• 4. Possible side effects
• 5. How to store Connettivina
• 6. Contents of the pack and other information

1. What Connettivina is and what it is used for

Connettivina 2 mg/ ml cutaneous spray contains the active ingredient sodium hyaluronate, a substance
naturally produced by our body. Local supply of hyaluronic acid facilitates the process of
healing of lesions.
Connettivina 2 mg/ ml cutaneous spray is a medicine for topical (local) use indicated for the treatment of:

• abrasions, scratches, superficial wounds, burns, minor burns and small cuts, more or less deep, including those that may affect both the nipple and the areola, i.e. the surrounding skin area (nipple cracks);
• localized skin irritations caused by sun, cold, wind, diaper rash, irritation and dehydration of the skin following radiotherapy (medical therapy that uses high-energy radiation to destroy cancer cells);
• as an adjunct, skin lesions (ulcers) due to circulatory disorders and wounds characterized by a difficult healing process, such as pressure sores.

Consult your doctor if you do not feel better or if you feel worse after a few days.

2. What you need to know before using Connettivina

Do not use Connettivina:
if you are allergic to the active ingredient or to any of the other ingredients of this medicine (listed in
section 6).

Warnings and precautions
Consult your doctor or pharmacist before using Connettivina.
Connettivina is for external use only.
The use of Connettivina, especially if prolonged, may lead to sensitization (allergic
reactions). If this occurs, stop treatment and consult your doctor who will prescribe a
suitable therapy.

Other medicines and Connettivina
Tell your doctor or pharmacist if you are taking, have recently taken or might take any
other medicines.
Do not use Connettivina at the same time as disinfectants containing quaternary ammonium salts.

Pregnancy and breastfeeding
If you are pregnant, suspect you are pregnant, or are planning a pregnancy, or if you are breastfeeding,
ask your doctor or pharmacist for advice before using this medicine.
Connettivina can be used during pregnancy and breastfeeding.

Driving and using machines
Connettivina does not impair the ability to drive vehicles or operate machinery.

Connettivina 2 mg/ mlcutaneous spray contains methyl p-hydroxybenzoateand propyl p-hydroxybenzoatewhich
may cause allergic reactions (including delayed reactions).

3. How to use Connettivina

Use this medicine following exactly as stated in this leaflet or as instructed by your doctor or pharmacist. If you have any doubts, consult your doctor or pharmacist.
Before applying Connettivina, carefully clean and disinfect the skin area to be treated.
Wounds resulting from vascular ulcers and pressure sores should preferably be cleaned with
physiological solution (NaCl 0.9%); if necessary, surgical cleaning should be performed. Subsequently
wounds should preferably be disinfected with povidone-iodine or chlorhexidine. Quaternary ammonium
solutions should be avoided.
Apply Connettivina 2 mg/ml cutaneous spray 2 or 3 times a day, in a sufficient quantity to cover the
affected skin area. Deliver the Connettivina spray solution evenly onto the lesion. After
application, cover with appropriate dressing if necessary.
Use Connettivina only for short periods of treatment. Do not exceed the indicated dose.
Consult your doctor if symptoms persist after a short period of treatment or, at any time, if
they worsen.

If you use more Connettivina than you should
In case of accidental use of an excessive dose of Connettivina, immediately inform your doctor or
go to the nearest hospital.
No cases of intoxication due to the use of an excessive amount of
Connettivina have ever been reported.

If you forget to use Connettivina
If you have forgotten to apply the cutaneous spray, do so as soon as you remember. Then continue
application according to the usual schedule.

If you stop using Connettivina
If you have any doubts about the use of this medicine, consult your doctor or pharmacist.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.
Local reactions, including allergic type reactions, have been observed.

Reporting of side effects
If you get any side effects, talk to your doctor or pharmacist. You can also report side effects directly through the national reporting system at the address: http://www.agenziafarmaco.it/it/responsabili .
By reporting side effects you can help provide more information on the safety of
this medicine.

5. How to store Connettivina

Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the packaging after “Scad”. The expiry date refers to the last day of that month.
The expiry date indicated refers to the medicine in intact packaging, correctly stored.
Store at a temperature below 30°C.
Do not dispose of any medicine in wastewater or household waste. Ask your pharmacist how to dispose of
medicines you no longer use. This will help protect the environment.

6. Contents of the pack and other information

What Connettivina contains
The active ingredient is sodium hyaluronate.
1 ml of solution contains 2 mg of sodium hyaluronate. Each 20 ml bottle of Connettivina
cutaneous spray contains 40 mg of sodium hyaluronate.
The other ingredients are: sodium chloride, methyl parahydroxybenzoate, propyl parahydroxybenzoate, purified water.

Description of the appearance of Connettivina and contents of the pack
Connettivina cutaneous spray is presented in the form of a solution contained in a 20 ml bottle, of amber type I glass, equipped with a plastic nebulizer closed with a polyethylene cap.

Marketing Authorisation Holder and manufacturer

Marketing Authorisation Holder
Fidia Farmaceutici S.p.A.
Via Ponte della Fabbrica, 3/A
35031 Abano Terme (PD)

Manufacturer
Fidia Farmaceutici S.p.A.
Via Ponte della Fabbrica, 3/A
35031 Abano Terme (PD)

Connettivina 2 mg impregnated gauzes, 4 mg impregnated gauzes, 12 mg impregnated gauzes

Sodium hyaluronate

Read this leaflet carefully before using this medicine as it contains important
information for you.
Always use this medicine exactly as described in this leaflet or as your doctor or pharmacist has
told you.

• Keep this leaflet. You may need to read it again.
• If you want more information or advice, ask your pharmacist.
• If any side effects occur, including those not listed in this leaflet, tell your doctor or pharmacist. See section 4.
• See a doctor if you do not feel better or if your symptoms worsen after a short period of treatment.

Contents of this leaflet:

• 1. What Connettivina is and what it is used for
• 2. What you need to know before using Connettivina
• 3. How to use Connettivina
• 4. Possible side effects
• 5. How to store Connettivina
• 6. Contents of the pack and other information

1. What Connettivina is and what it is used for

Connettivina garze contains the active ingredient sodium hyaluronate, a substance naturally produced
by our body. Local administration of hyaluronic acid facilitates the healing process of
lesions.
Connettivina garze is a medicine for topical use indicated for the treatment of:

• healing of abrasions, scratches, superficial wounds, burns, minor burns and small cuts, more or less deep, including those that may affect both the nipple and the areola, i.e. the surrounding skin area (nipple cracks);
• localized skin irritations caused by sun, cold, wind, diaper rash, irritation and dehydration of the skin following radiotherapy (medical therapy that uses high-energy radiation to destroy cancer cells);
• as an adjunct, skin lesions (ulcers) due to blood circulation disorders and wounds characterized by a difficult healing process, such as pressure ulcers.

See your doctor if you do not feel better or if you feel worse after a few days.

2. What you need to know before using Connettivina

Do not use Connettivina:
If you are allergic to the active ingredient or to any of the other ingredients of this medicine (listed in
section 6).

Warnings and precautions
Consult your doctor or pharmacist before using Connettivina.
Connettivina is for external use only.
The use of Connettivina, especially if prolonged, may lead to sensitization (allergic
reactions). If this occurs, stop treatment and consult your doctor who will prescribe a
suitable therapy.

Other medicines and Connettivina
Tell your doctor or pharmacist if you are taking, have recently taken or might take any
other medicine.
Do not use Connettivina at the same time with disinfectants containing quaternary ammonium salts.
e

Pregnancy and breastfeeding
If you are pregnant, suspect you may be pregnant, or are planning a pregnancy, or if you are breastfeeding,
ask your doctor or pharmacist for advice before using this medicine.
Connettivina can be used during pregnancy and breastfeeding.

Driving and operating machinery
Connettivina does not affect the ability to drive vehicles or operate machinery.

Connettivina 2 mg impregnated gauze, Connettivina 4 mg impregnated gauze and Connettivina 12 mg gauze
impregnated contain polyethylene glycol 4000. It may cause skin irritation.

4. How to use Connettivina

Use this medicine following exactly as stated in this leaflet or as instructed by your doctor or pharmacist. If you have any doubts, consult your doctor or pharmacist.
Before applying Connettivina, carefully clean and disinfect the skin area to be treated.
Wounds resulting from vascular ulcers and pressure sores should preferably be cleaned with
physiological solution (NaCl 0.9%); if necessary, surgical cleaning should be performed. Subsequently,
wounds should preferably be disinfected with povidone-iodine or chlorhexidine. Quaternary ammonium
solutions should be avoided.
Take the gauze from the sealed sachet, being careful to touch only one end. Apply 1 or more
medicated gauzes, depending on the size of the area to be treated. If necessary, cover the gauze with a
suitable bandage. Replace the gauzes 2 or 3 times a day.
Use Connettivina only for short periods of treatment. Do not exceed the indicated dose.
Consult your doctor if symptoms persist after a short period of treatment or, at any time, if
they worsen.

If you use more Connettivina than you should
In case of accidental use of an excessive dose of Connettivina, immediately inform your doctor or
go to the nearest hospital.
No cases of intoxication due to the use of an excessive amount of
Connettivina have ever been reported.

If you forget to use Connettivina
If you forgot to apply the gauze, do so as soon as you remember. Then continue application
according to the usual schedule.

If you stop using Connettivina
If you have any doubts about the use of this medicine, consult your doctor or pharmacist.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.
Local reactions, including those of an allergic type, have been observed.

Reporting of side effects
If you experience any side effects, including those not listed in this leaflet, please inform your
doctor or pharmacist. You can also report side effects directly through the national reporting system at: http://www.agenziafarmaco.it/it/responsabili .
By reporting side effects you can help provide more information on the safety of
this medicine.

5. How to store Connettivina

Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the packaging after “Exp”. The expiry date refers to the last day of that month.
The expiry date indicated refers to the medicine in intact packaging, correctly stored.
Store at a temperature below 30°C.
Do not dispose of any medicine in wastewater or household waste. Ask your pharmacist how to dispose of
medicines you no longer use. This will help protect the environment.

7. Package contents and other information

What Connettivina contains

Connettivina 2 mg Impregnated Gauzes

• The active ingredient is sodium hyaluronate. Each gauze is impregnated with 4 g of cream containing 2 mg of sodium hyaluronate.
• The other ingredients are: glycerol, polyethylene glycol 4000, purified water.

Connettivina 4 mg Impregnated Gauzes
The active ingredient is sodium hyaluronate.
Each gauze is impregnated with 8 g of cream containing 4 mg of sodium hyaluronate.
The other ingredients are: glycerol, polyethylene glycol 4000, purified water.

Connettivina 12 mg Impregnated Gauzes
The active ingredient is sodium hyaluronate 12.
Each gauze is impregnated with 24 g of cream containing 12 mg of sodium hyaluronate.
The other ingredients are: glycerol, polyethylene glycol 4000, purified water.

Description of the appearance of Connettivina and package contents

Connettivina 2 mg Impregnated Gauzes
One package contains 10 sterile impregnated gauzes of 10x10 cm, contained in a single sealed sachet of
aluminium-polyethylene paper.

Connettivina 4 mg Impregnated Gauzes
One package contains 10 sterile impregnated gauzes of 10x20 cm, contained in a single sealed sachet of
aluminium-polyethylene paper.

Connettivina 12 mg Impregnated Gauzes
One package contains 5 sterile impregnated gauzes of 20x30 cm, contained in a single sealed sachet of
aluminium-polyethylene paper.

Marketing Authorisation Holder and Manufacturer

Marketing Authorisation Holder
Fidia Farmaceutici S.p.A.
Via Ponte della Fabbrica, 3/A
35031 Abano Terme (PD)

Manufacturer
Fidia Farmaceutici S.p.A.
Via Ponte della Fabbrica, 3/A
35031 Abano Terme (PD)

Connettivina 2 mg/g gel

Sodium hyaluronate

Read this leaflet carefully before using this medicine as it contains important
information for you.
Always use this medicine exactly as described in this leaflet or as your doctor or pharmacist has told you.

• Keep this leaflet. You may need to read it again.
• If you want more information or advice, ask your pharmacist.
• If any side effects occur, including those not listed in this leaflet, tell your doctor or pharmacist. See section 4.
• See a doctor if you do not feel better or if your symptoms worsen after a short period of treatment.

Contents of this leaflet:

• 1. What Connettivina is and what it is used for
• 2. What you need to know before using Connettivina
• 3. How to use Connettivina
• 4. Possible side effects
• 5. How to store Connettivina
• 6. Contents of the pack and other information

1. What is Connettivina and what is it used for

Connettivina 2 mg/g gel contains the active ingredient sodium hyaluronate, a substance naturally
produced by our body. Local supply of hyaluronic acid facilitates the healing process
of lesions.
Connettivina 2 mg/g gel is a medicine for topical (local) use indicated for the treatment of:

• abrasions, scratches, superficial wounds, burns, minor burns and small cuts, including those that may affect both the nipple and the surrounding areola, i.e. the surrounding skin area (nipple cracks);
• localized skin irritations caused by sun, cold, wind, diaper rash, irritation and dehydration of the skin following radiotherapy (medical therapy that uses high-energy radiation to destroy cancer cells); Consult your doctor if you do not feel better or if you feel worse after a few days.

2. What you need to know before using Connettivina

Do not use Connettivina:
if you are allergic to the active ingredient or to any of the other ingredients of this medicine (listed in
section 6).

Warnings and precautions
Consult your doctor or pharmacist before using Connettivina.
Connettivina is for external use only.
The use of Connettivina, especially if prolonged, may lead to sensitization phenomena (allergic
reactions). If this should occur, discontinue treatment and consult your doctor who will prescribe a
suitable therapy.

Other medicines and Connettivina
Tell your doctor or pharmacist if you are taking, have recently taken, or might take any
other medicines.
Do not use Connettivina at the same time as disinfectants containing quaternary ammonium salts.

Pregnancy and breastfeeding
If you are pregnant, suspect you are pregnant, or are planning a pregnancy, or if you are breastfeeding,
ask your doctor or pharmacist for advice before using this medicine.
Connettivina can be used during pregnancy and breastfeeding.

Driving and operating machinery
Connettivina does not impair the ability to drive vehicles or operate machinery.

Connettivina 2 mg/g gel contains methyl parahydroxybenzoateand propyl parahydroxybenzoatewhich may
cause allergic reactions (including delayed reactions).

5. How to use Connettivina

Use this medicine following exactly as stated in this leaflet or as instructed by your doctor or pharmacist. If you have any doubts, consult your doctor or pharmacist.
Before applying Connettivina, carefully clean and disinfect the area of skin to be treated.
Apply Connettivina 2 mg/g gel 2 or 3 times a day, in a sufficient quantity to cover the affected skin area.
Spread a uniform layer of gel. After application, cover with an appropriate bandage, if necessary.
Use Connettivina only for short periods of treatment. Do not exceed the indicated dose.
Consult your doctor if symptoms persist after a short period of treatment or, at any time, if they worsen.

If you use more Connettivina than you should
In case of accidental use of an excessive dose of Connettivina, immediately inform your doctor or go to the nearest hospital.
There have never been reports of poisoning due to the use of an excessive amount of Connettivina.

If you forget to use Connettivina
If you forgot to apply the gel, do so as soon as you remember. Then continue application according to the usual schedule.

If you stop using Connettivina
If you have any doubts about the use of this medicine, consult your doctor or pharmacist.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.
Local reactions, including those of an allergic type, have been observed.

Reporting of side effects
If you experience any side effects, including those not listed in this leaflet, please inform your
doctor or pharmacist. You can also report side effects directly through the national reporting system at: http://www.agenziafarmaco.it/it/responsabili .
By reporting side effects you can help provide more information on the safety of
this medicine.

5. How to store Connettivina

Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the packaging after “Exp”. The expiry date
refers to the last day of that month.
The expiry date indicated refers to the medicine in intact packaging, correctly stored.
Store at a temperature below 25°C.
Do not dispose of any medicine in wastewater or household waste. Ask your pharmacist how to dispose of
medicines you no longer use. This will help protect the environment.

8. Package Contents and Other Information

What Connettivina contains
The active ingredient is sodium hyaluronate.
1 g of gel contains 2 mg of sodium hyaluronate. Each 30 g tube of gel contains 60 mg of
hyaluronic acid.
The other components are: non-crystallizable sorbitol 70%, methyl p-hydroxybenzoate, propyl p-
hydroxybenzoate, carbomer 940, sodium hydroxide, purified water.

Description of the appearance of Connettivina and package contents
Connettivina is a transparent gel dispensed in a 30 g aluminum tube.

Marketing Authorisation Holder and Manufacturer

Marketing Authorisation Holder
Fidia Farmaceutici S.p.A.
Via Ponte della Fabbrica, 3/A
35031 Abano Terme (PD)

Manufacturer
Fidia Farmaceutici S.p.A.
Via Ponte della Fabbrica, 3/A
35031 Abano Terme (PD)

Connettivina 2 mg/g cream

Sodium hyaluronate

Read this leaflet carefully before using this medicine as it contains important
information for you.
Always use this medicine exactly as described in this leaflet or as your doctor or pharmacist has told you.

• Keep this leaflet. You may need to read it again.
• If you want more information or advice, ask your pharmacist.
• If any side effects occur, including those not listed in this leaflet, tell your doctor or pharmacist. See section 4.
• See a doctor if you do not improve or if your symptoms worsen after a short period of treatment.

Contents of this leaflet:

• 1. What Connettivina is and what it is used for
• 2. What you need to know before using Connettivina
• 3. How to use Connettivina
• 4. Possible side effects
• 5. How to store Connettivina
• 6. Contents of the pack and other information

1. What is Connettivina and what is it used for

Connettivina 2 mg/g cream contains the active ingredient sodium hyaluronate, a substance naturally
produced by our body. Local administration of hyaluronic acid facilitates the healing process
of lesions.
Connettivina 2 mg/g cream is a medicine for topical (local) use indicated for the treatment of:

• abrasions, scratches, superficial wounds, burns, minor burns and small cuts, including those that may affect both the nipple and the surrounding areola (breast fissures);
• localized skin irritations caused by sun, cold, wind, diaper rash, irritation and dehydration of the skin following radiotherapy (medical therapy that uses high-energy radiation to destroy cancer cells). Consult your doctor if you do not feel better or if you feel worse after a few days.

2. What you need to know before using Connettivina

Do not use Connettivina:
if you are allergic to the active ingredient or any of the other ingredients of this medicine (listed in
section 6).

Warnings and precautions
Consult your doctor or pharmacist before using Connettivina.
Connettivina is for external use only.
Use of Connettivina, especially if prolonged, may lead to sensitization phenomena (allergic
reactions). If this occurs, stop treatment and consult your doctor who will prescribe appropriate
therapy.

Other medicines and Connettivina
Tell your doctor or pharmacist if you are taking, have recently taken, or might take any
other medicines.
Do not use Connettivina at the same time as disinfectants containing quaternary ammonium salts.

Pregnancy and breastfeeding
If you are pregnant, suspect you are pregnant, or are planning a pregnancy, or if you are breastfeeding,
ask your doctor or pharmacist for advice before using this medicine.
Connettivina can be used during pregnancy and breastfeeding.

Driving and using machines
Connettivina does not impair the ability to drive vehicles or operate machinery.

Connettivina 2 mg/g cream contains methyl p-hydroxybenzoateand propyl p-hydroxybenzoatewhich may
cause allergic reactions (including delayed reactions).

Connettivina 2 mg/g cream contains polyethylene glycol 400 monostearate. It may cause skin irritation.

6. How to use Connettivina

Use this medicine following exactly as stated in this leaflet or as instructed by your doctor or pharmacist. If you have any doubts, consult your doctor or pharmacist.
Before applying Connettivina, carefully clean and disinfect the area of skin to be treated.
Apply Connettivina 2 mg/g cream 2 or 3 times a day, in a sufficient quantity to cover the affected skin area. Spread a uniform layer of cream. After applying the medication, cover, if necessary, with appropriate bandages.
Use Connettivina only for short periods of treatment. Do not exceed the indicated dose.
Consult your doctor if symptoms persist after a short period of treatment or, at any time, if they worsen.

If you use more Connettivina than you should
In case of accidental use of an excessive dose of Connettivina, immediately inform your doctor or go to the nearest hospital.
No cases of poisoning due to the use of an excessive amount of Connettivina have ever been reported.

If you forget to use Connettivina
If you forgot to apply the cream, do so as soon as you remember. Then continue application according to the usual schedule.

If you stop using Connettivina
If you have any doubts about the use of this medicine, consult your doctor or pharmacist.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.
Local reactions, including allergic type reactions, have been observed.

Reporting of side effects
If you get any side effects, talk to your doctor or pharmacist. You can also report side effects directly through the national reporting system at: http://www.agenziafarmaco.it/it/responsabili .
By reporting side effects you can help provide more information on the safety of
this medicine.

5. How to store Connettivina

Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the packaging after “Scad”. The expiry date refers to the last day of that month.
The expiry date indicated refers to the medicine in intact packaging, correctly stored.
Store at a temperature below 30°C.
Do not dispose of any medicine in wastewater or household waste. Ask your pharmacist how to dispose of
medicines you no longer use. This will help protect the environment.

9. Contents of the pack and other information

What Connettivina contains
The active ingredient is sodium hyaluronate.
1 g of Connettivina cream contains 2 mg of sodium hyaluronate.
The other ingredients are: polyethylene glycol 400 monostearate, decyl oleate, emulsifying wax
glycerol, sorbitol solution 70%, methyl p-hydroxybenzoate, propyl p-hydroxybenzoate, flavour (Dalin PH), purified water.

Description of the appearance of Connettivina and contents of the pack
Connettivina is a white cream contained in an aluminium tube of 15 g, 30 g or 100 g.
Not all pack sizes may be marketed.

Marketing Authorisation Holder and Manufacturer

Marketing Authorisation Holder
Fidia Farmaceutici S.p.A.
Via Ponte della Fabbrica, 3/A
35031 Abano Terme (PD)

Manufacturer
Fidia Farmaceutici S.p.A.
Via Ponte della Fabbrica, 3/A
35031 Abano Terme (PD)